sodium phenylbutyrate

Drug ingredient

CAS 1716-12-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 1716-12-7 — 1 Na⁺

US productionNot reported

Import value, 2024$84M

Top sourceChina 63%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291639 · basket

These shares come from HS customs code 291639, which covers 229 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 63%ChinaIT 19%ItalyIN 8%IndiaDE 4%GermanyCH 3%Switzerland

Spain
Ukraine
Singapore
Turkey
Norway
Czech Republic
Taiwan
South Korea
Japan
Mexico
New Zealand
Canada
Sweden
Hong Kong
Latvia

19 FDA-registered drug labelers

Apothecon Pharmaceuticals Pvt Ltd

AX Pharmaceutical Corp

CU Chemie Uetikon GmbH

DARMERICA, LLC

ENDO USA, Inc.

GLENMARK PHARMACEUTICALS INC., USA

Horizon Therapeutics USA, Inc.

MEDISCA INC.

Medunik USA

NURAY CHEMICALS PRIVATE LIMITED

Par Active Technologies Private Limited

Patheon Inc.

PCAS

Rottendorf Pharma GmbH

Sigmapharm Laboratories, LLC

Sri Krishna Pharmaceuticals Ltd. Unit I

STHREE CHEMICALS PRIVATE LIMITED

SYNFINE DRUGS PRIVATE LIMITED

Zydus Pharmaceuticals USA Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

•Sodium Phenylbutyrate
•Buphenyl
•Pheburane

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$3.48/gCombi-Blocks, Inc.

CountryUnited States

Pack$1740.00 / 500 g

Purity97%

Vendors20 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

19 more vendors

Vendor	Country	$/g	Pack	Purity
Chemscene	United States	$4.64	100 g	—
BLD Pharmatech Co., Limited	United States	$5.80	100 g	98%
BLD Pharmatech GmbH	Germany	$5.80	100 g	98%
BLD Pharmatech Ltd.	China	$5.80	100 g	98%
Ambeed, Inc.	United States	$5.80	100 g	98%
AK Scientific Specialized	United States	$5.80	100 g	95%
AK Scientific, Inc.	United States	$7.77	100 g	98%
Fluorochem EU	Germany	$11.13	5 g	98%
AstaTech (2 weeks)	United States	$15.64	25 g	97%
Cayman Europe	Estonia	$23.44	10 g	98%
MedKoo Biosciences, Inc	United States	$55.00	10 g	98%
Molnova	China	$260.00	500 mg	99%
TargetMol Chemicals	China → United States	$288.00	500 mg	99.99%
Apexbio Technology LLC	United States	$400.00	200 mg	99.78%
MedChemExpress MCE	Sweden	$665.50	200 mg	99.86%
TargetMol Chemicals EU	Austria	$760.00	50 mg	99.99%
Sigma-Aldrich (Rush Stock)	Germany	$1305.90	100 mg	98%
Sigma-Aldrich	Germany	$1305.90	100 mg	98%
Key Organics Ltd.	United Kingdom	$6900.00	10 mg	98%

Chemical Identity

CAS1716-12-7

PubChem CID5258

DTXSIDDTXSID7040948

FormulaC10H11NaO2

Mol. Weight186.18 g/mol

SMILESC1=CC=C(C=C1)CCCC(=O)[O-].[Na+]

Data Sources

PubChem · compound 5258Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

sodium phenylbutyrate (CAS 1716-12-7) https://chemicalindependence.com/chemical/1716-12-7/ PubChem: 5258. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5258 FDA National Drug Code directory: CAS 1716-12-7. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 291639 for CAS 1716-12-7. Reporting year: 2024. https://usatrade.census.gov/