Sildenafil citrate

Drug ingredient

CAS 171599-83-0

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$2.0B

Top sourceIreland 63%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293590 · basket

These shares come from HS customs code 293590, which covers 182 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 63%IrelandSG 14%SingaporeIN 7%IndiaCN 7%ChinaCH 2%Switzerland

Portugal
Spain
Italy
Austria
Israel
Hungary
Canada
South Korea
Netherlands
Finland
Poland
Indonesia
Ukraine
Mexico
South Africa
Croatia
Greece
Taiwan
Hong Kong

85 FDA-registered drug labelers

A-S Medication Solutions

Actavis Pharma, Inc.

Advagen Pharma Ltd

Advanced Rx of Tennessee, LLC

Advanced Rx Pharmacy of Tennessee, LLC

Ajanta Pharma USA Inc.

Almon Healthcare Private Limited

American Health Packaging

Amneal Pharmaceuticals LLC

Amneal Pharmaceuticals NY LLC

Amneal Pharmaceuticals of New York LLC

Amoli Organics (A Division of Umedica Laboratories Pvt.Ltd.)

ANI Pharmaceuticals, Inc.

Aphena Pharma Solutions - Tennessee, LLC

Appco Pharma LLC

Ascend Laboratories, LLC

Asclemed USA, Inc.

Aurobindo Pharma Limited

AvKARE

AvPAK

AX Pharmaceutical Corp.

Azico Biophore India Private Limited

BluePoint Laboratories

Bostal LLC

Bryant Ranch Prepack

Cadila Pharmaceuticals Limited

Camber Pharmaceuticals, Inc.

Cardinal Health 107, LLC

Chartwell RX, LLC

CIPLA USA INC.,

Cutyx Research LLP

DARMERICA, LLC

DIRECT RX

Eugia US LLC

Evereen Shanghai Biotechnology Ltd.

Exelan Pharmaceuticals, Inc.

Fagron Inc

Haleos Labs Limited

HEC Pharm USA Inc.

Hetero Drugs Limited

IBSA Pharma Inc.

Jubilant Cadista Pharmaceuticals Inc.

KALCHEM INTERNATIONAL INC

LETCO MEDICAL, LLC

Lupin Pharmaceuticals, Inc.

Macleods Pharmaceuticals Limited

Maithili Life Sciences Private Limited

Major Pharmaceuticals

Matrix Pharmacorp Private Limited

MEDISCA Inc.

Modavar Pharmaceuticals LLC

MSN Organics Private Limited

Mylan Pharmaceuticals Inc.

Northstar Rx LLC

Northwind Health Company, LLC

Novadoz Pharmaceuticals LLC

NuCare Pharmaceuticals, Inc.

PD-Rx Pharmaceuticals, Inc.

PFIZER LABORATORIES DIV PFIZER INC

Pharma Source Direct, Inc.

Preferred Pharmaceuticals Inc.

Professional Compounding Centers of America dba PCCA

Proficient Rx LP

Quallent Pharmaceuticals Health LLC

Raks Pharma Pvt. Limited

REMEDYREPACK INC.

Reyoung Corporation

SCH Global Services Private Limited

SHOOLIN PHARMA CHEM LLP

SMS Pharmaceuticals Limited

Spectrum Laboratory Products, Inc.

Supriya Lifescience Limited

Teva Pharmaceuticals USA, Inc.

Torrent Pharmaceuticals Limited

TruPharma LLC

Viatris Specialty LLC

Virtus Pharmaceuticals, LLC

Willow Birch Pharma, Inc.

Willow Birch Pharma, LLC

Xenex Laboratories Inc

XLCARE Pharmaceuticals INC.

Yaral Pharma Inc.

ZAKLADY FARMACEUTYCZNE POLPHARMA S A

Zydus Lifesciences Limited

Zydus Pharmaceuticals (USA) Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 5 drug and cosmetic product listings (FDA).

•Sildenafil Citrate
•Vybrique
•Sildenafil
•Viagra
•Revatio

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS171599-83-0

PubChem CID135413523

DTXSIDDTXSID4046076

FormulaC28H38N6O11S

Mol. Weight666.7 g/mol

SMILESCCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

Data Sources

PubChem · compound 135413523Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Sildenafil citrate (CAS 171599-83-0) https://chemicalindependence.com/chemical/171599-83-0/ PubChem: 135413523. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/135413523 FDA National Drug Code directory: CAS 171599-83-0. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293590 for CAS 171599-83-0. Reporting year: 2024. https://usatrade.census.gov/