aprepitant
Drug ingredientThis chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.
Where It Comes From
19 FDA-registered drug labelers
Alivus Life Sciences Limited
BluePoint Laboratories
Dr. Reddy's Laboratories Limited
Glenmark Pharmaceuticals Inc., USA
Golden State Medical Supply, Inc.
Heron Therapeutics, Inc.
Hetero Drugs Limited
Inke SA
Jubilant Biosys limited
Merck Sharp & Dohme LLC
MSN Pharmachem Private Limited
Novo Nordisk Production Ireland Limited
OLON ACTIVE PHARMACEUTICAL INGREDIENTS INDIA PRIVATE LIMITED
Optimus Drugs Private Limited
Piramal Pharma Limited
Sandoz Inc
SOLARA ACTIVE PHARMA SCIENCES LIMITED
Torrent Pharmaceuticals Limited
Wisdom Pharmaceutical Co.,Ltd.
Why It Matters
Sectors
Health
Downstream Uses
Appears in 4 drug and cosmetic product listings (FDA).
- •Emend
- •Aprepitant
- •Cinvanti
- •Aponvie
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No Shortage
Shortage History
Each row is a separate manufacturer's FDA shortage filing — not a timeline for the drug as a whole. Multiple "current" entries are normal: each manufacturer/NDC files independently. Status reflects the manufacturer's report; reason describes their supply situation (Available, Unavailable, or to be discontinued).
to be discontinued
Aprepitant Oral Powder for Suspension
04/08/2026Chemical Identity
CAS170729-80-3
PubChem CID135413536
DTXSIDDTXSID3049047
FormulaC23H21F7N4O3
Mol. Weight534.4 g/mol
SMILESCC(C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)OC2C(N(CCO2)CC3=NNC(=O)N3)C4=CC=C(C=C4)F
Data Sources
1354135362026-04-07
https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/name/aprepitant/cids/JSON
Archive: data/sources/pubchem_name/aprepitant.json
CAS 170729-80-32026-04-25
https://open.fda.gov/data/ndc/
Archive: data/sources/fda/ndc/ndc.json
CAS 170729-80-32026-06-13
https://api.fda.gov/drug/shortages.json
Archive: data/sources/fda/shortages/shortages.json