Cosyntropin

Drug ingredient

CAS 16960-16-0

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$16.4B

Top sourceIreland 94%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293719 · basket

These shares come from HS customs code 293719, which covers 53 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 94%IrelandAR 4%ArgentinaCN 1%ChinaDK 1%Denmark

Switzerland
Sweden
India
Spain
Israel
Austria
Belgium
Netherlands
Italy
Hong Kong
Brazil
United Kingdom
Germany
Canada
Australia
Japan
New Zealand
Latvia
South Korea
Taiwan
Estonia
Uruguay

8 FDA-registered drug labelers

Amphastar Pharmaceuticals, Inc.

Bachem AG

BCN PEPTIDES SA

Henry Schein, Inc.

HF Acquisition Co LLC, DBA HealthFirst

Medical Purchasing Solutions, LLC

Polypeptide Laboratories Inc

Sandoz Inc

Why It Matters

Sectors

Health

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•Cosyntropin
•Cortrosyn

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS16960-16-0

PubChem CID16129617

DTXSIDDTXSID201014470

FormulaC136H210N40O31S

Mol. Weight2933.4 g/mol

SMILESCC(C)C(C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)N1CCCC1C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(C(C)C)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)N3CCCC3C(=O)O)NC(=O)C4CCCN4C(=O)C(CCCCN)NC(=O)CNC(=O)C(CC5=CNC6=CC=CC=C65)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CC8=CNC=N8)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CO)NC(=O)C(CC9=CC=C(C=C9)O)NC(=O)C(CO)N

Data Sources

PubChem · compound 16129617Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Cosyntropin (CAS 16960-16-0) https://chemicalindependence.com/chemical/16960-16-0/ PubChem: 16129617. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/16129617 FDA National Drug Code directory: CAS 16960-16-0. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293719 for CAS 16960-16-0. Reporting year: 2024. https://usatrade.census.gov/