calcium hexafluorosilicate

Drug ingredient

CAS 16925-39-6

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 16925-39-6 — 1 Ca²⁺

US productionNot reported

Import value, 2024$87M

Top sourceChina 71%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 282690 · basket

These shares come from HS customs code 282690, which covers 32 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 71%ChinaKR 12%South KoreaJP 5%JapanDE 4%GermanyBE 3%Belgium

Denmark
Mexico
Taiwan
Spain
Canada
Bulgaria
Vietnam
Poland
Italy
Brazil
United Kingdom
Switzerland

14 FDA-registered drug labelers

Apex Energetics Inc.

Bestmade Natural Products

BM Private Limited

Boiron

Carolinas Weight Loss Institute

Deseret Biologicals, Inc.

DNA Labs, Inc.

Eight and Company L.L.C

Energique, Inc.

Liddell Laboratories, Inc.

Nutritional Specialties, Inc.

ProBlen

Professional Complementary Health Formulas

Seroyal USA

Why It Matters

Sectors

Health

Downstream Uses

Appears in 23 drug and cosmetic product listings (FDA).

•Thyroid HP
•Sixth Chakra (Third Eye) 7306
•Party Relief
•Thyroid Liquescence 3021
•Renal Drops 5024
•A03 Ultra Antitox
•Fuligo
•Party Detox

Show all 23

•C08 Calcium Metabolism
•Thyroid Sarcode
•Lapis albus
•HKI
•C07 Strong Ligaments AND Joints
•Bestmade Natural Products BM60
•Weight Loss Support Plus Thyroid
•Thyroid Liquescence
•PEMF Optimizer
•Thyropro
•HTHY
•Thyro Drops 5028
•D-51
•Fifth Chakra (Throat) 7305
•C02 Fibrozolve

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS16925-39-6

PubChem CID10176392

DTXSIDDTXSID60884944

FormulaCaF6Si

Mol. Weight182.15 g/mol

SMILESF[Si-2](F)(F)(F)(F)F.[Ca+2]

Data Sources

PubChem · compound 10176392Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

calcium hexafluorosilicate (CAS 16925-39-6) https://chemicalindependence.com/chemical/16925-39-6/ PubChem: 10176392. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/10176392 EPA TSCA Inventory: CAS 16925-39-6. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 282690 for CAS 16925-39-6. Reporting year: 2024. https://usatrade.census.gov/