Spinosad

Drug ingredient

CAS 168316-95-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$459M

Top sourceGermany 33%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 380891 · basket

These shares come from HS customs code 380891, which covers 10 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

DE 33%GermanyMX 14%MexicoCN 9%ChinaIN 8%IndiaCA 5%Canada

Dominican Republic
Spain
Czech Republic
United Kingdom
Portugal
Sweden
Colombia
Philippines
Turkey
New Zealand
Peru
Uruguay
Costa Rica
Kenya
Slovenia
Monaco
South Africa
Belgium
El Salvador
Australia
Chile
Panama
Hong Kong

6 FDA-registered drug labelers

Allegis Pharmaceuticals, LLC

Cipher Pharmaceuticals Inc.

Elanco US Inc.

Hubei Honch Pharmaceutical Co., Ltd.

ParaPRO LLC

Quimica Sintetica S.A.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•Spinosad
•Natroba

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS168316-95-8

PubChem CID17754356

DTXSIDDTXSID7032478

FormulaC83H132N2O20

Mol. Weight1477.9 g/mol

SMILESCCC1CCCC(C(C(=O)C2=CC3C4CC(CC4C=CC3C2CC(=O)O1)OC5C(C(C(C(O5)C)OC)OC)OC)C)OC6CCC(C(O6)C)N(C)C.CCC1CCCC(C(C(=O)C2=CC3C4CC(CC4C(=CC3C2CC(=O)O1)C)OC5C(C(C(C(O5)C)OC)OC)OC)C)OC6CCC(C(O6)C)N(C)C

Data Sources

PubChem · compound 17754356Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Spinosad (CAS 168316-95-8) https://chemicalindependence.com/chemical/168316-95-8/ PubChem: 17754356. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/17754356 FDA National Drug Code directory: CAS 168316-95-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 380891 for CAS 168316-95-8. Reporting year: 2024. https://usatrade.census.gov/