Desmopressin

Drug ingredientActive Shortage

CAS 16679-58-6

This drug ingredient is in active FDA shortage. At least one manufacturer cannot meet demand.

US productionNot reported

Import value, 2024$16.4B

Top sourceIreland 94%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293719 · basket

These shares come from HS customs code 293719, which covers 53 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 94%IrelandAR 4%ArgentinaCN 1%ChinaDK 1%Denmark

Switzerland
Sweden
India
Spain
Israel
Austria
Belgium
Netherlands
Italy
Hong Kong
Brazil
United Kingdom
Germany
Canada
Australia
Japan
New Zealand
Latvia
South Korea
Taiwan
Estonia
Uruguay

4 FDA-registered drug labelers

Aspen Oss B.V.

Pharma Source Direct, Inc.

Piramal Pharma Limited

PolyPeptide Laboratories (Sweden) AB

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

Active Shortage

Shortage History

Rows group FDA shortage filings by drug product. Each manufacturer makes its own FDA shortage filing, so one product can carry several reports at once: Available, Limited Availability, Unavailable or to be discontinued.

Current shortage
Desmopressin Acetate Spray
Shortage listed since March 12, 2021
Manufacturer reports: 1 unavailable, 1 available

See all current drug shortages

Chemical Identity

CAS16679-58-6

PubChem CID5311065

DTXSIDDTXSID1048259

FormulaC46H64N14O12S2

Mol. Weight1069.2 g/mol

SMILESC1CC(N(C1)C(=O)C2CSSCCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)N

Data Sources

PubChem · compound 5311065Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA Drug ShortagesRetrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Desmopressin (CAS 16679-58-6) https://chemicalindependence.com/chemical/16679-58-6/ PubChem: 5311065. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5311065 FDA National Drug Code directory: CAS 16679-58-6. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 16679-58-6. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293719 for CAS 16679-58-6. Reporting year: 2024. https://usatrade.census.gov/