N-(Isobutoxymethyl)acrylamide

CAS 16669-59-3

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$371M

Top sourceChina 27%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292419 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports 44.1K lb

These shares come from HS customs code 292419, which covers 211 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 27%ChinaIN 18%IndiaDE 14%GermanyIT 10%ItalyGB 6%United Kingdom

Hungary
Austria
Spain
Egypt
Canada
Sweden
Ukraine
Denmark
Israel
Lithuania
Greece
Ireland
Taiwan
Uruguay
Turkey
Australia
Singapore
Latvia
Colombia

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Allnex Usa

Why It Matters

Sectors

Plastics & Rubber

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Paint additives and coating additives not described by other categories in Plastics Material and Resin Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.56/gCombi-Blocks, Inc.

CountryUnited States

Pack$280.00 / 500 g

Purity98%

Vendors4 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

3 more vendors

Vendor	Country	$/g	Pack	Purity
A2B Chem LLC	United States	$0.60	500 g	98%
AA BLOCKS	United States	$0.64	500 g	98%
Labotest KG	Germany	$453.00	1000 mg	90%

Chemical Identity

CAS16669-59-3

PubChem CID27979

DTXSIDDTXSID2044848

FormulaC8H15NO2

Mol. Weight157.21 g/mol

SMILESCC(C)COCNC(=O)C=C

Data Sources

EPA CompTox (DSSTox) · DTXSID2044848Retrieved 2026-04-06
PubChem · compound 27979Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

N-(Isobutoxymethyl)acrylamide (CAS 16669-59-3) https://chemicalindependence.com/chemical/16669-59-3/ EPA CompTox (DSSTox): DTXSID2044848. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID2044848 PubChem: 27979. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/27979 EPA Chemical Data Reporting: 16669-59-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 16669-59-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292419 for CAS 16669-59-3. Reporting year: 2024. https://usatrade.census.gov/