Metaxalone

Drug ingredient

CAS 1665-48-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 1665-48-1
US productionNot reported
Import value, 2024$6.4B
Top sourceSingapore 36%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293499 · basket

These shares come from HS customs code 293499, which covers 575 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
SG 36%SingaporeIE 23%IrelandCN 11%ChinaCH 6%SwitzerlandIN 5%India
38 FDA-registered drug labelers
A-S Medication Solutions
Actavis Pharma, Inc.
Advanced Rx of Tennessee, LLC
Advanced Rx Pharmacy of Tennessee, LLC
American Health Packaging
Amneal Pharmaceuticals LLC
Amneal Pharmaceuticals of New York LLC
Angelini Pharma Italia Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. Spa
Asclemed USA, Inc.
AvKARE
AvPAK
BluePoint Laboratories
Bryant Ranch Prepack
Chunghwa Chemical Synthesis & Biotech. Ltd
CIPLA USA INC.
COHANCE LIFESCIENCES LIMITED
DIRECT RX
Doc Rx
Dr. Reddys Laboratories Limited
Hetero Drugs Limited
INA Pharmaceutics Inc
Lannett Company, Inc.
Lee Pharma Limited
Major Pharmaceuticals
Misemer Pharmaceuticals, Inc.
Northwind Health Company, LLC
PD-Rx Pharmaceuticals, Inc.
PHOENIX RX LLC
Preferred Pharmaceuticals Inc.
Proficient Rx LP
Quality Care Products, LLC
Raks Pharma Pvt. Limited
REMEDYREPACK INC.
ScieGen Pharmaceuticals, Inc.
Sportpharm LLC
St. Mary's Medical Park Pharmacy
Syn-Tech Chem. & Pharm. Co., Ltd.
Zhejiang Apeloa Jiayuan Pharmaceutical Co., Ltd.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Metaxalone
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$1.55/gCombi-Blocks, Inc.
CountryUnited States
Pack$775.00 / 500 g
Purity98%
Vendors28 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS1665-48-1
PubChem CID15459
DTXSIDDTXSID3023269
FormulaC12H15NO3
Mol. Weight221.25 g/mol
SMILESCC1=CC(=CC(=C1)OCC2CNC(=O)O2)C

Data Sources

Brief citations

Metaxalone (CAS 1665-48-1) https://chemicalindependence.com/chemical/1665-48-1/ PubChem: 15459. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/15459 FDA National Drug Code directory: CAS 1665-48-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293499 for CAS 1665-48-1. Reporting year: 2024. https://usatrade.census.gov/