Tetraisopropyl methylenediphosphonate

CAS 1660-95-3

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$598M

Import volumeZero

Top sourceChina 89%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293149 · basket

EPA reports by year

2023: US production Confidential · Imports Zero
2019: US production Zero · Imports Zero

These shares come from HS customs code 293149, which covers 114 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 89%ChinaIN 4%IndiaCA 3%CanadaDE 2%GermanyAR 1%Argentina

United Kingdom
Italy
Mexico
Japan
Switzerland
Hong Kong
Ukraine
Finland
Sweden
Spain
Poland
Slovakia
Netherlands
Singapore
Taiwan
South Korea
Czech Republic

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Lanxess

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in Pharmaceutical and Medicine Manufacturing (100%)Use—non-incorporative activities

Chemical Identity

CAS1660-95-3

PubChem CID74266

DTXSIDDTXSID7044847

FormulaC13H30O6P2

Mol. Weight344.32 g/mol

SMILESCC(C)OP(=O)(CP(=O)(OC(C)C)OC(C)C)OC(C)C

Data Sources

EPA CompTox (DSSTox) · DTXSID7044847Retrieved 2026-04-06
PubChem · compound 74266Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Tetraisopropyl methylenediphosphonate (CAS 1660-95-3) https://chemicalindependence.com/chemical/1660-95-3/ EPA CompTox (DSSTox): DTXSID7044847. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID7044847 PubChem: 74266. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/74266 EPA Chemical Data Reporting: 1660-95-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 1660-95-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293149 for CAS 1660-95-3. Reporting year: 2024. https://usatrade.census.gov/