FD&C Red 3

CAS 16423-68-0

Companies reported imports and no US production of this chemical to EPA for 2023.

US productionZero

Import value, 2024$56M

Import volume108.0K lb

Import dependency100%

Top sourceIndia 70%

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

FD&C Red 3 · US import value by year

2013: $63M · Peak 2022: $90M · 2024: $56M · 2025: $58M

Where It Comes From

Customs basis: HS 320412 · basket

EPA reports by year

2023: US production Zero · Imports 108.0K lb
2019: US production Confidential · Imports 61.3K lb

These shares come from HS customs code 320412, which covers 106 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IN 70%IndiaMY 7%MalaysiaCH 4%SwitzerlandCN 4%ChinaDE 3%Germany

Ireland
United Kingdom
Spain
South Korea
Denmark
Pakistan
Hong Kong
Czech Republic
Brazil
Turkey

EPA-registered importers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Target

Why It Matters

Sectors

Textiles

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Dyes in Synthetic Dye and Pigment Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.80/gAngene Chemical

CountryChina (registered: Hong Kong)

Pack$20.00 / 25 g

PurityNot recorded

Vendors14 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

13 more vendors

Vendor	Country	$/g	Pack	Purity
Angene International Limited	United States	$2.43	250 g	96%
A2B Chem LLC	United States	$2.52	25 g	98.02%
Aaron Chemicals LLC	Hong Kong	$2.68	25 g	—
AA BLOCKS	United States	$2.68	25 g	—
Fulfilled by Molport	Latvia	$8.00	1 g	96%
AK Scientific, Inc.	United States	$8.76	25 g	95%
Sigma-Aldrich (Rush Stock)	Germany	$11.02	25 g	—
Sigma-Aldrich	Germany	$11.02	25 g	—
Molnova	China	$123.00	1 g	99%
TargetMol Chemicals	China → United States	$137.00	1 g	98.77%
Labotest KG	Germany	$217.80	5000 mg	90%
MedChemExpress MCE	Sweden	$871.20	100 mg	99.07%
Angene	China → Hong Kong	$4266.67	30 mg	—

Chemical Identity

CAS16423-68-0

PubChem CID3259

DTXSIDDTXSID7021233

FormulaC20H8I4O5

Mol. Weight835.9 g/mol

SMILESC1=CC=C2C(=C1)C(=O)OC23C4=CC(=C(C(=C4OC5=C(C(=C(C=C35)I)O)I)I)O)I

Data Sources

EPA CompTox (DSSTox) · DTXSID7021233Retrieved 2026-04-06
PubChem · compound 3259Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

FD&C Red 3 (CAS 16423-68-0) https://chemicalindependence.com/chemical/16423-68-0/ EPA CompTox (DSSTox): DTXSID7021233. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID7021233 PubChem: 3259. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/3259 EPA Chemical Data Reporting: 16423-68-0. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 16423-68-0. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 320412 for CAS 16423-68-0. Reporting year: 2024. https://usatrade.census.gov/