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isosorbide mononitrate

Drug ingredient

CAS 16051-77-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 16051-77-7
US productionNot reported
Import value, 2024$3.5B
Top sourceIreland 57%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293299 · basket

These shares come from HS customs code 293299, which covers 229 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 57%IrelandNL 24%NetherlandsCH 8%SwitzerlandCN 5%ChinaIT 2%Italy
24 FDA-registered drug labelers
A-S Medication Solutions
Actavis Pharma, Inc.
American Health Packaging
ANI Pharmaceuticals, Inc.
Aphena Pharma Solutions - Tennessee, LLC
Aurobindo Pharma Limited
Bryant Ranch Prepack
Cardinal Health 107, LLC
Chartwell RX, LLC
Coupler LLC
Dipharma Francis Srl
Edenbridge Pharmaceuticals LLC.
Golden State Medical Supply, Inc.
Ingenus Pharmaceuticals, LLC
Lannett Company, Inc.
Major Pharmaceuticals
NCS HealthCare of KY, LLC dba Vangard Labs
Northwind Health Company, LLC
NuCare Pharmaceuticals, Inc.
OMNIVIUM PHARMACEUTICALS LLC.
Proficient Rx LP
REMEDYREPACK INC.
Shandong New Time Pharmaceutical Co., Ltd.
Torrent Pharmaceuticals Limited

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Isosorbide Mononitrate
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS16051-77-7
PubChem CID27661
DTXSIDDTXSID9023176
FormulaC6H9NO6
Mol. Weight191.14 g/mol
SMILESC1C(C2C(O1)C(CO2)O[N+](=O)[O-])O

Data Sources

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Brief citations

isosorbide mononitrate (CAS 16051-77-7) https://chemicalindependence.com/chemical/16051-77-7/ PubChem: 27661. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/27661 FDA National Drug Code directory: CAS 16051-77-7. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293299 for CAS 16051-77-7. Reporting year: 2024. https://usatrade.census.gov/