Hemin

Drug ingredient

CAS 16009-13-5

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 16009-13-5 — 1 Fe²⁺

US productionNot reported

Import value, 2024$1.4B

Top sourceIreland 33%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293399 · basket

These shares come from HS customs code 293399, which covers 518 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 33%IrelandCN 26%ChinaIN 11%IndiaDE 9%GermanyIT 4%Italy

Taiwan
Poland
Canada
Ivory Coast
Greece
Hungary
Indonesia
Latvia
Belgium
Slovakia
Czech Republic
Austria
Netherlands
Finland
Denmark
Croatia
Australia
South Africa
Sweden
Hong Kong
Malta
Singapore
Lithuania
Malaysia
Oman
Serbia

2 FDA-registered drug labelers

PCAS Finland Oy

Recordati Rare Diseases, Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Panhematin

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$1776.00/gMolnova

CountryChina

Pack$888.00 / 500 mg

Purity99%

Vendors4 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

3 more vendors

Vendor	Country	$/g	Pack	Purity
TargetMol Chemicals	China → United States	$1974.00	500 mg	99.99%
TargetMol Chemicals EU	Austria	$4550.00	100 mg	99.99%
AstaTech (2 weeks)	United States	$6050.00	100 mg	95%

Chemical Identity

CAS16009-13-5

PubChem CID26945

DTXSIDDTXSID9037662

FormulaC34H32FeN4O4

Mol. Weight616.5 g/mol

SMILESCC1=C(C2=CC3=C(C(=C([N-]3)C=C4C(=C(C(=N4)C=C5C(=C(C(=N5)C=C1[N-]2)C)C=C)C)C=C)C)CCC(=O)O)CCC(=O)O.[Fe+2]

Data Sources

PubChem · compound 26945Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Hemin (CAS 16009-13-5) https://chemicalindependence.com/chemical/16009-13-5/ PubChem: 26945. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/26945 EPA TSCA Inventory: CAS 16009-13-5. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293399 for CAS 16009-13-5. Reporting year: 2024. https://usatrade.census.gov/