Diroximel Fumarate

Drug ingredient

CAS 1577222-14-0

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$43M

Top sourceJapan 25%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292519 · basket

These shares come from HS customs code 292519, which covers 43 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

JP 25%JapanCN 21%ChinaGB 21%United KingdomAT 14%AustriaDE 7%Germany

Australia
Belgium
Israel
Switzerland
Hungary
Ukraine
Slovakia
Singapore

7 FDA-registered drug labelers

Biogen Inc.

Dr. Reddy's Laboratories Limited

Honour Lab Limited

MSN Life Sciences Private Limited

Novo Nordisk Production Ireland Limited

Sterling Pharma Solutions Limited

TAPI Croatia Industries Ltd.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Vumerity

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS1577222-14-0

PubChem CID73330464

DTXSIDDTXSID101026181

FormulaC11H13NO6

Mol. Weight255.22 g/mol

SMILESCOC(=O)C=CC(=O)OCCN1C(=O)CCC1=O

Data Sources

PubChem · compound 73330464Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Diroximel Fumarate (CAS 1577222-14-0) https://chemicalindependence.com/chemical/1577222-14-0/ PubChem: 73330464. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/73330464 FDA National Drug Code directory: CAS 1577222-14-0. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292519 for CAS 1577222-14-0. Reporting year: 2024. https://usatrade.census.gov/