Ibuprofen
Drug ingredientCAS 15687-27-1
This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$84M
Import volumeZero
Top sourceChina 63%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 291639 · basket
EPA reports by year
- 2023
- US production Confidential · Imports Zero
These shares come from HS customs code 291639, which covers 229 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
Source Countries
Country of origin for US imports, from Census customs data (2024).
CN 63%ChinaIT 19%ItalyIN 8%IndiaDE 4%GermanyCH 3%Switzerland
- Spain
- Ukraine
- Singapore
- Turkey
- Norway
- Czech Republic
- Taiwan
- South Korea
- Japan
- Mexico
- New Zealand
- Canada
- Sweden
- Hong Kong
- Latvia
EPA-registered manufacturers (2)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Basf Se · DE Germany
Basf
264 FDA-registered drug labelers
7-Eleven
A-S Medication Solutions
AAA Pharmaceutical, Inc.
AAFES/Your Military Exchanges
Acme United Corporation
Actavis Pharma, Inc.
Adare Pharmaceuticals, Inc.
Advagen Pharma Ltd.
ADVANCED FIRST AID, INC.
Advanced Rx of Tennessee, LLC
Advanced Rx Pharmacy of Tennessee, LLC
Aero Healthcare
AFT Pharmaceuticals US, Inc.
AiPing Pharmaceutical, Inc.
Albertsons Companies
Allegiant Health
Amazon.com Services LLC
American Health Packaging
American Sales Company
AMERIFOODS TRADING COMPANY
AMERISOURCE BERGEN
Amneal Pharmaceuticals LLC
Amneal Pharmaceuticals NY LLC
Amneal Pharmaceuticals of New York LLC
Aphena Pharma Solutions - Tennessee, LLC
AptaPharma Inc.
Army & Air Force Exchange Service
ARMY AND AIR FORCE EXCHANGE SERVICE
Ascend Laboratories, LLC
Ascent Pharmaceuticals, Inc.
Asclemed USA Inc.
Athlete's Needs, Inc.
ATLANTIC BIOLOGICALS CORP.
Aurobindo Pharma Limited
Aurohealth LLC
Aurolife Pharma, LLC
BASF Corporation
BASF SE
Basic Drugs, Inc.
Belmora LLC
Best Choice
Best Choice (Valu Merchandisers Company)
BETTER LIVING BRANDS LLC.
BI-MART
BIONPHARMA INC.
BJWC
BJWC (Berkley & Jensen / BJ's)
BluePoint Laboratories
Boswell Pharmacy Services LLC d/b/a BPS Wholesale
Breeden Brothers, LLC
Brisk Pharmaceuticals
Bryant Ranch Prepack
Camber Consumer Care Inc
Camber Pharmaceuticals, Inc.
CARDINAL HEALTH
Cardinal Health (Leader) 70000
Cardinal Health 107, LLC
CARDINAL HEALTH 110, LLC DBA LEADER
Care One (American Sales Company)
Care One (Retail Business Services, LLC.)
CATALENT ARGENTINA S.A.I.C.
Catalent Argentina S.A.I.y.C
Catalent Pharma Solutions, LLC
Chain Drug Consortium
Chain Drug Consortium, LLC
CHAIN DRUG MARKETING ASSOCIATION INC
Chalkboard Health
Chartwell RX, LLC
Cintas Corporation
Conney Safety Products, LLC
Contract Pharmacal Corp.
Costco Wholesale
Costco Wholesale Company
COSTCO WHOLESALE CORPORATION
Coupler LLC
Cumberland Pharmaceuticals Inc.
CVS
CVS Pharmacy
CVS PHARMACY, INC.
DEMOULAS SUPERMARKETS INC.
DIRECT RX
DISCOUNT DRUG MART
DISCOUNT DRUG MART, INC.
Doc Rx
DOLGENCORP INC
Dolgencorp, Inc. (DOLLAR GENERAL & REXALL)
DOLGENCORP, LLC
Dr. Reddy's Laboratories Inc
Dr. Reddy's Laboratories Limited
Dr. Reddy's Labortories Inc
ENDO USA, Inc.
EQUATE (WAL-MART STORES, INC.)
EQUATE (Wal-Mart Stores, Inc.) (see also WAL-MART INC)
EXELAN PHARMACEUTICALS, INC.
Family Dollar
Family Dollar (FAMILY WELLNESS)
Family Dollar Services Inc
Farmacias De Similares TX LLC
Florida Pharmaceutical Products, LLC
FSA STORE INC.
FSA Store Inc. (Caring Mill)
FSA Store Inc. (Caring Mills)
Geri-Care Pharmaceutical Corp
Geritrex LLC
GLENMARK THERAPEUTICS INC., USA
Gobrands, Inc
Golden State Medical Supply, Inc.
Good Sense (Geiss, Destin & Dunn, Inc.)
Granules India Limited
Granules India Ltd
Granules Pharmaceuticals Inc.
GRANULES USA, INC.
Grocery Outlet, Inc.
Guardian Drug Company
H E B
Haleon US Holdings LLC
Harris Teeter
Harris Teeter, LLC
HART Health
Health Pharma USA LLC
HealthLife of USA LLC
Henry Schein Inc.
Hikma Pharmaceuticals USA Inc
Hubei Biocause Heilen Pharmaceutical Co., Ltd
Humanwell PuraCap Pharmaceutical (Wuhan) Co., Ltd
Humanwell PuraCap Pharmaceuticals (Wuhan) Co., Ltd
HYVEE INC
INGLES MARKETS, INC.
IOL Chemicals and Pharmaceuticals Ltd.
JC World Bell Wholesale Co., Inc.
JHK Inc dba American Safety & First Aid
Jones Healthcare Group - Packaging Services, Inc
Kai Squared
Kenvue Brands LLC
Kesin Pharma Corporation
KROGER COMPANY
L Perrigo Company
L.N.K. International, Inc.
LEADER/ Cardinal Health 110, Inc.
Legacy Pharmaceutical Packaging, LLC
LETCO MEDICAL, LLC
Lidl US LLC
Lil Drug Store Products, Inc
Live Betr LLC
Major Pharmaceuticals
MARC GLASSMAN, INC.
MARKSANS PHARMA LIMITED
McKesson Medical-Surgical
Medisca Inc.
Medline industries, LP
MEIJER DISTRIBUTION INC.
Meijer, Inc.
Mollec Inc
Morning Star OTC
Navajo Manufacturing Company Inc.
NCS HealthCare of KY, LLC dba Vangard Labs
New World Imports
Northwind Health Company, LLC
NuCare Pharmaceuticals Inc.
Ohm Laboratories Inc.
OPMX LLC
P & L Development, LLC
Padagis Israel Pharmaceuticals Ltd
PAI Holdings, LLC dba PAI Pharma
Particle Dynamics International, LLC
Patheon Softgels Inc.
PD-Rx Pharmaceuticals, Inc.
Pharmaceutical Associates, Inc.
Pharmadel LLC
PharmPak, Inc.
PHOENIX RX LLC
PLD Acquisitions LLC DBA Avma Pharma Solutions
Precision Dose Inc.
Preferred Pharmaceuticals Inc.
Premier Value Alliance LLC
Professional Complementary Health Formulas
Professional Compounding Centers of America
Professional Compounding Centers of America dba PCCA
Proficient Rx LP
PROSTAT FIRST AID
Provision Medical Products
PUBLIX SUPER MARKETS INC
PURACAP PHARMACEUTICAL LLC
Puro Pharma Inc.
QPharma Inc
Quality Care Products, LLC
R J General Corporation
RANDOB LABS,LTD. DBA CROSSINGWELL CONSUMER HEALTH
Randob Labs., Ltd.
RAONBIO CORP
Recipharm pharmaservices Private Limited
Redicare LLC
Redpharm Drug
RedPharm Drug, Inc.
Reliable 1 Laboratories LLC
REMEDYREPACK INC.
RETAIL BUSINESS SERVICES , LLC.
RITE AID
RITE AID CORPORATION
RUGBY LABORATORIES
Rugby Laboratories, Inc.
Safeway
Safeway, Inc.
Salado Sales, Inc.
SAM'S WEST INC
Select Consumer Group
Shandong Xinhua Pharmaceutical Co Ltd.
Shandong Xinhua Pharmaceutical Company Limited
Shield Pharmaceuticals Corp
SI Group, Inc.
SKYA HEALTH, LLC
SMS Pharmaceuticals Limited
Sofgen Pharmaceuticals LLC
Softgel Healthcare Private Limited
SOLA Pharmaceuticals, LLC
SOLARA ACTIVE PHARMA SCIENCES LIMITED
Southern Sales & Services, Inc.
SpecGx LLC
Spectrum Laboratory Products, Inc.
SPI Pharma Inc
Spirit Pharmaceutical LLC
SPIRIT PHARMACEUTICALS LLC
Sportpharm LLC
Sportpharm, Inc. dba Sportpharm
ST. MARY'S MEDICAL PARK PHARMACY
Strategic Sourcing Services
Strategic Sourcing Services LLC
Strides Pharma Inc
Strides Pharma Science Limited
Strides Shasun Limited
Strive Pharmaceuticals Inc.
Sun Pharmaceutical Industries, Inc.
TARGET CORPORATION
TARO PHARMACEUTICALS U.S.A., INC.
Teeter
The Kroger Co.
The Kroger Company
Thompson Safety
TIME CAP LABORATORIES, INC
TOP CARE (Topco Associates LLC)
TOPCO ASSOCIATES LLC
Trifecta Pharmaceuticals USA LLC
TWIN MED LLC
Uline
Unifirst First Aid
Unifirst First Aid Corporation
Unishield
United Natural Foods, Inc. dba UNFI
VALU MERCHANDISERS COMPANY
Viona Pharmaceuticals Inc
WAL-MART STORES INC.
WALGREEN CO.
WALGREEN COMPANY
WALGREENS
WALGREENS CO.
WALMART INC.
WALMART INC. (see also Equate)
Westminster Pharmaceuticals, LLC
Whole Foods Market, INC.
Wildman Business Group
WINCO FOODS, LLC
WR Group, Inc.
Zibo Xinhua - Perrigo Pharmaceutical Co., Ltd
Zydus Lifesciences Limited
Why It Matters
Sectors
Health
Downstream Uses
Appears in 228 drug and cosmetic product listings (FDA).
- •Redicare Ibuprofen 200mg
- •Ibuprofen
- •basic care ibuprofen pm
- •Basic Care Childrens Ibuprofen
- •Childrens Ibuprofen
- •Advil PM
- •Childrens Advil
- •Junior Strength Advil
Show all 228
- •pain relief
- •Goodnow PAIN Relief
- •Up and Up childrens ibuprofen
- •Ibuprofen Childrens
- •Ibuprofen PM
- •Dual Action
- •Signature Care Ibuprofen
- •good sense ibuprofen childrens
- •Acetaminophen 250 mg and Ibuprofen 125 mg
- •Good Sense Childrens Ibuprofen
- •Topcare Ibuprofen
- •care one ibuprofen
- •careone childrens ibuprofen
- •Acetaminophen and Ibuprofen
- •Green Guard Ibupro relief
- •Medi-First Ibuprofen
- •parents choice infants ibuprofen
- •equate ibuprofen pm
- •good sense ibuprofen
- •IBU
- •Childrens Ibuprofen bubblegum
- •Infants Ibuprofen
- •Dolex Children
- •dg health dual back pain reliever
- •dg health ibuprofen
- •Ibuprofen and Pseudoephedrine Hydrochloride
- •Ibuprofen Immediate Release
- •Ibuprofen and famotidine
- •Childrens Ibuprofen Oral Suspension
- •Caldolor
- •Circle K Ibuprofen
- •Ibuprofen, Lil Drug Store, 24ct
- •Advil
- •Dye Free Ibuprofen
- •Ibuprofen minis
- •Dye Free Childrens Ibuprofen
- •Ibuprofen infants Drops
- •dye-free pain relief
- •Leader Ibuprofen
- •leader infants ibuprofen
- •Ibuprofen 200 mg
- •Ibuprofen Oral
- •foster and thrive dual action
- •basic care infants ibuprofen
- •Basic Care Dual Action
- •Acetaminophen, Ibuprofen
- •Advil DUAL Action WITH Acetaminophen Back Pain
- •dual pain reliever
- •betr pain relief
- •up and up ibuprofen pm
- •Ibuprofen, Diphenhydramine HCL
- •up and up ibuprofen
- •Hydrocodone Bitartrate and Ibuprofen
- •Ibuprofen and Diphenhydramine Citrate
- •Good Neighbor Pharmacy Childrens Ibuprofen
- •good neighbor pharmacy ibuprofen
- •Congestion Relief
- •Medique at Home Iprin
- •Dover Addaprin
- •Equate Ibuprofen
- •Ibuprofen Mini Dye Free Advil
- •Dolex Flex
- •dg health childrens ibuprofen
- •rexall ibuprofen
- •Childrens Ibuprofen Oral Suspension, Dye Free
- •kirkland signature ibuprofen ib
- •Ibuprofen, Caseys, 50ct
- •Motrin IB, CVP Health
- •Ibuprofen 24/7 Life by 7-Eleven
- •Ibuprofen IB
- •Advil Sinus Congestion and Pain Relief
- •ibuprofen 200
- •Leader Childrens Ibuprofen
- •Ibuprofen and Pseudoephedrine HCl
- •Foster and Thrive Ibuprofen
- •Pain Relief - Ibuprofen 200 mg
- •basic care ibuprofen
- •Ibuprofen Thompson
- •Advil COLD AND Sinus
- •Advil Allergy Sinus
- •Advil Allergy and Congestion Relief
- •Concentrated ibuprofen infants
- •good sense dual action
- •signature care infants ibuprofen
- •signature care childrens ibuprofen
- •good sense ibuprofen pm
- •Equaline ibuprofen childrens
- •ibuprofen infants
- •equate ibuprofen childrens
- •Motrin IB
- •Infants Motrin
- •Childrens Motrin
- •Acetaminophen and Ibuprofen Back Pain
- •Ibuprofen, Lil Drug Store, 50ct
- •Uline Ibuprofen
- •Pain Reliever
- •Acetaminophen
- •DUAL Action BACK PAIN Reliever
- •equate pain reliever
- •equate dual pain reliever
- •Kosher Meds Dye-Free Ibuprofen
- •Physicians Care Ibuprofen
- •up and up dye free infants concentrated ibuprofen
- •equaline ibuprofen
- •Xpect Ibuprofen
- •Proprinal
- •Motrin Infants
- •Ibuprofen (Nsaid) Pain Releiver/ Fever Reducer
- •DG health dual pain reliever
- •Diphenhydramine HCl and Ibuprofen
- •Ibuprofen Pain Reliever/Fever Reducer
- •Ibuprofen, Solubilized 24/7 Life by 7-Eleven
- •Advil Liquigels
- •Dye-Free Ibuprofen 200
- •Assured Ibuprofen
- •childrens ibuprofen 100
- •Combogesic
- •Dual Action Pain Relief
- •pain relief pm
- •dual action pain reliever
- •Fast Pain Relief
- •Ibuwin Forte
- •Aacetaminophen and Ibuprofen
- •foster and thrive childrens ibuprofen ib
- •GOOD Remedies ibuprofen 200 mg
- •Acetaminophen and Ibuprofen (Nsaid)
- •Signature Care Ibuprofen PM
- •Good Sense ibuprofen infants
- •Topcare Ibuprofen PM
- •Medique Iprin
- •Ibuprofen Dye-Free
- •Unishield Ibuprofen
- •Motrin Dual Action With Tylenol
- •Careall Ibuprofen
- •Ibuprofen Pain Releiver/ Fever Reducer
- •Exchange Select Ibuprofen PM
- •dg health Ibuprofen pm
- •profen ib
- •Ibuprofen, Caseys 4good
- •Advil Dual Action with Acetaminophen
- •Childrens Ibuprofen 100 Dye Free
- •Berkley and Jensen Ibuprofen
- •Topcare Dual Action Back Pain
- •Childrens Ibuprofen Grape
- •betr remedies ibuprofen
- •Period Pills by Biikay
- •pain relief ibuprofen
- •Advil PM- diphenhydramine citrate and ibuprofen tablet, coated
- •Good Sense Dual Action Back Pain
- •topcare childrens ibuprofen
- •care one ibuprofen childrens
- •good neighbor pharmacy ibuprofen pm
- •Medi-First Plus Ibuprofen
- •AeroTab Ibuprofen
- •Childrens Ibuprofen 572
- •Advil Dual Action with Acetaminophen, Travel Basix
- •Motrin IB, Travel Basix
- •Advil PM, Travel Basix
- •Advil PM, CVP Health
- •Foster and Thrive Infants Ibuprofen
- •equate dual back pain reliever
- •Combogesic IV
- •equaline ibuprofen pm
- •365 whole foods market ibuprofen
- •Direct Safety Ibuprofen
- •Pain Formula Drops 2046
- •Lil Drug Store Ibuprofen
- •Cabinet Pain Reliever and Fever Reducer
- •McKesson Ibuprofen 200 mg
- •Flex-Prin
- •Dual Back Pain Reliever
- •Right Remedies Ibuprofen 200 MG
- •Ibuprofen 100
- •Infants Advil
- •Kosher MEDS
- •Topcare Infants Ibuprofen
- •Care One Ibuprofen PM
- •Sudafed PE Head Congestion Plus Pain
- •CVS Ibuprofen
- •Childrens Ibuprofen fruit
- •Childrens Ibuprofen blue raspberry
- •Ibuprofen mini
- •profen ib infants
- •Ibuprofen 200 mg and Diphenhydramine Citrate 38 mg
- •Migraine Relief
- •Ibuprofen Famotidine
- •Ibuprofen 250
- •Childrens Ibuprofen Oral Suspension Original Berry Flavor
- •Advil Liquigel
- •Ibuprofen CA
- •equaline childrens ibuprofen
- •Green Guard Ibuprofen Relief
- •Motrin IB Migraine
- •Motrin PM
- •Pediacare Childrens Ibuprofen Berry
- •Ibuprofen and Diphenhydramine HCl
- •Sound Body Ibuprofen
- •Leader Dual Action Pain Reliever
- •Henry Schein Ibuprofen
- •Amazon Basic CARE Ibuprofen PM
- •Careone DUAL Action
- •Advil Multi-Symptom Cold and Flu
- •Good Neighbor Pharmacy ibuprofen childrens
- •Childrens Flanax ORAL
- •equaline dual action pain reliever
- •Equaline congestion relief
- •profen IB childrens
- •Childrens Ibuprofen Oral Suspension, Bubble Gum
- •kirkland signature ibuprofen
- •Ibuprofen, Circle K, 50ct
- •Ibuprofen, Lil Drug Store
- •Valumeds Ibuprofen
- •Ibuprofen Fast relief medicine for pain
- •Ibuprofen Migraine
- •Leader Ibuprofen PM
- •foster and thrive ibuprofen pm
- •Amazon Basic CARE Ibuprofen
- •topcare dual action
- •Advil Migraine
- •Advil Sinus Congestion AND PAIN
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
- •Intermediate in Pharmaceutical and Medicine ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
Vendor Pricing
$0.04/gAaron Chemicals LLC
CountryHong Kong
Pack$36.00 / 1 kg
Purity98%
Vendors40 available
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
39 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| Angene Chemical | China → Hong Kong | $0.04 | 500 g | 98% |
| A2B Chem LLC | United States | $0.06 | 1 kg | 97% |
| AA BLOCKS | United States | $0.07 | 1 kg | 97% |
| Chemscene | United States | $0.08 | 1 kg | — |
| BLD Pharmatech Co., Limited | United States | $0.09 | 1 kg | 98% |
| BLD Pharmatech GmbH | Germany | $0.09 | 1 kg | 98% |
| BLD Pharmatech Ltd. | China | $0.09 | 1 kg | 98% |
| Ambeed, Inc. | United States | $0.09 | 1 kg | 98% |
| Fluorochem UK | United Kingdom | $0.09 | 1 kg | 99% |
| Fluorochem EU | Germany | $0.09 | 1 kg | 99% |
| AK Scientific Specialized | United States | $0.25 | 1 kg | 95% |
| Combi-Blocks, Inc. | United States | $0.25 | 1 kg | 98% |
| AK Scientific, Inc. | United States | $0.33 | 1 kg | 98% |
| AstaTech, Inc | United States | $0.38 | 100 g | 97% |
| Angene International Limited | United States | $0.68 | 500 g | 98% |
| Fulfilled by Molport | Latvia | $1.00 | 5 g | 98% |
| MedKoo Biosciences, Inc | United States | $18.00 | 25 g | 98% |
| Apexbio Technology LLC | United States | $18.40 | 5 g | 99.17% |
| Interbioscreen | Hong Kong | $25.50 | 10 g | 95% |
| Cayman Europe | Estonia | $27.13 | 10 g | 99% |
| MedChemExpress MCE | Sweden | $29.77 | 5 g | 99.97% |
| Sigma-Aldrich (Rush Stock) | Germany | $31.61 | 5 g | — |
| Sigma-Aldrich | Germany | $31.61 | 5 g | — |
| Molnova | China | $48.00 | 1 g | 99% |
| TargetMol Chemicals | China → United States | $53.00 | 1 g | 99.81% |
| Eximed | Ukraine | $120.00 | 1 g | 95% |
| Vitas M Chemical Limited | Hong Kong | $225.00 | 1 g | 90% |
| Otava, Ltd. | Ukraine | $225.00 | 1 g | 95% |
| Labotest KG | Germany | $453.00 | 1000 mg | 90% |
| Angene | China → Hong Kong | $2500.00 | 30 mg | 99% |
| Otava, Ltd. (2 weeks) | Ukraine | $2724.00 | 50 mg | 90% |
| Princeton BioMolecular Research (SC) | United States | $2900.00 | 100 mg | 90% |
| Life Chemicals Inc. | Ukraine → Canada | $3466.67 | 75 mg | 90% |
| ChemBridge Corporation | Kazakhstan | $4800.00 | 50 mg | 90% |
| ChemDiv, Inc. | United States | $5480.00 | 50 mg | 90% |
| Key Organics Ltd. | United Kingdom | $6900.00 | 10 mg | 97% |
| Combi-Blocks (back-ordered) | United States | $8400.00 | 100 mg | 95% |
| TimTec, LLC | United States | $9333.33 | 30 mg | 90% |
| AstaTech (2 weeks) | United States | $12200.00 | 25 mg | 95% |
Chemical Identity
CAS15687-27-1
PubChem CID3672
DTXSIDDTXSID5020732
FormulaC13H18O2
Mol. Weight206.28 g/mol
SMILESCC(C)CC1=CC=C(C=C1)C(C)C(=O)O
Data Sources
- PubChem · compound 3672Retrieved 2026-04-07
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- FDA National Drug Code directoryRetrieved 2026-04-07
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Ibuprofen (CAS 15687-27-1) https://chemicalindependence.com/chemical/15687-27-1/ PubChem: 3672. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/3672 EPA Chemical Data Reporting: 15687-27-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 291639 for CAS 15687-27-1. Reporting year: 2024. https://usatrade.census.gov/