Drometrizole trisiloxane

Drug ingredient

CAS 155633-54-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Top sourceNo public record

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Where It Comes From

EPA and Census publish no US supply data for this chemical.

1 FDA-registered drug labeler

Guangzhou Yueyou Biological Technology Co., Ltd.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Centella Sunscreen SPF 50

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$2.62/gAaron Chemicals LLC

CountryHong Kong

Pack$262.00 / 100 g

Purity98%

Vendors12 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

11 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$2.65	100 g	98%
Combi-Blocks, Inc.	United States	$695.00	1 g	98%
TargetMol Chemicals	China → United States	$1034.00	500 mg	99.81%
TargetMol Chemicals EU	Austria	$1725.00	200 mg	99.81%
A2B Chem LLC (1 week)	United States	$2080.00	200 mg	98%
AA BLOCKS (1 week)	United States	$2195.00	200 mg	98%
Sigma-Aldrich (Rush Stock)	Germany	$2754.35	200 mg	—
Sigma-Aldrich	Germany	$2754.35	200 mg	—
Angene	China → Hong Kong	$4266.67	30 mg	98%
MedChemExpress MCE	Sweden	$12003.20	25 mg	98%
Angene International Limited	United States	$18120.00	25 mg	98%

Chemical Identity

CAS155633-54-8

PubChem CID9848888

DTXSIDDTXSID40431753

FormulaC24H39N3O3Si3

Mol. Weight501.8 g/mol

SMILESCC1=CC(=C(C(=C1)N2N=C3C=CC=CC3=N2)O)CC(C)C[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C

Data Sources

PubChem · compound 9848888Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07

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Brief citations

Drometrizole trisiloxane (CAS 155633-54-8) https://chemicalindependence.com/chemical/155633-54-8/ PubChem: 9848888. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/9848888 FDA National Drug Code directory: CAS 155633-54-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/