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Istradefylline

Drug ingredient

CAS 155270-99-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 155270-99-8
US productionNot reported
Import value, 2024$6M
Top sourceChina 50%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293959 · basket

These shares come from HS customs code 293959, which covers 9 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 50%ChinaIN 39%IndiaPL 6%PolandIT 4%ItalyDE 1%Germany
6 FDA-registered drug labelers
HONOUR LAB LIMITED
Kyowa Kirin, Inc.
Kyowa Pharma Chemical Co., Ltd.
MSN Life Sciences Private Limited
PROCOS SpA
TATEYAMA KASEI CO.,LTD.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Nourianz
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS155270-99-8
PubChem CID5311037
DTXSIDDTXSID7057652
FormulaC20H24N4O4
Mol. Weight384.4 g/mol
SMILESCCN1C2=C(C(=O)N(C1=O)CC)N(C(=N2)C=CC3=CC(=C(C=C3)OC)OC)C

Data Sources

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Brief citations

Istradefylline (CAS 155270-99-8) https://chemicalindependence.com/chemical/155270-99-8/ PubChem: 5311037. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5311037 FDA National Drug Code directory: CAS 155270-99-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293959 for CAS 155270-99-8. Reporting year: 2024. https://usatrade.census.gov/