Efavirenz

Drug ingredient

CAS 154598-52-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$6.4B

Top sourceSingapore 36%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293499 · basket

These shares come from HS customs code 293499, which covers 575 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

SG 36%SingaporeIE 23%IrelandCN 11%ChinaCH 6%SwitzerlandIN 5%India

Finland
Netherlands
Canada
Indonesia
Mexico
Taiwan
South Korea
Austria
Croatia
Sweden
Ukraine
Denmark
Israel
Czech Republic
New Zealand
Hong Kong
Kyrgyzstan
Australia
Portugal
South Africa
Poland
Slovenia
Brazil
Slovakia
Vietnam
Latvia
Malta
Hungary
Romania
Kenya
Belarus
Russia
Turkey
Norway

20 FDA-registered drug labelers

Aurobindo Pharma Limited

Bryant Ranch Prepack

Camber Pharmaceuticals, Inc.

Catalent Micron Technologies, Inc.

Cipla Ltd.

Cipla USA Inc.

Dasami Lab Private Limited

F.I.S. FABBRICA ITALIANA SINTETICI S.P.A.

Hetero Labs Limited

Jetpharma S.A.

Laurus Labs Limited

Macleods Pharmaceuticals Limited

Matrix Pharmacorp Private Limited

Siegfried St. Vulbas SAS

SMS Pharmaceuticals Limited

Takeda GmbH

Teva Pharmaceuticals USA, Inc.

Viatris Specialty LLC

XLCare Pharmaceuticals Inc.

Zhejiang Huahai Pharmaceutical Co., Ltd.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 4 drug and cosmetic product listings (FDA).

•Efavirenz
•Efavirenz, Emtricitabine and Tenofovir Disoproxil Fumarate
•Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate
•Symfi

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$51.00/gInterbioscreen

CountryHong Kong

Pack$510.00 / 10 g

Purity95%

Vendors5 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

4 more vendors

Vendor	Country	$/g	Pack	Purity
Vitas M Chemical Limited	Hong Kong	$310.00	1 g	90%
Princeton BioMolecular Research (SC)	United States	$2900.00	100 mg	90%
A2B Chem LLC (1 week)	United States	$59050.00	20 mg	—
AA BLOCKS (1 week)	United States	$62600.00	20 mg	—

Chemical Identity

CAS154598-52-4

PubChem CID64139

DTXSIDDTXSID9046029

FormulaC14H9ClF3NO2

Mol. Weight315.67 g/mol

SMILESC1CC1C#CC2(C3=C(C=CC(=C3)Cl)NC(=O)O2)C(F)(F)F

Data Sources

PubChem · compound 64139Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Efavirenz (CAS 154598-52-4) https://chemicalindependence.com/chemical/154598-52-4/ PubChem: 64139. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/64139 FDA National Drug Code directory: CAS 154598-52-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293499 for CAS 154598-52-4. Reporting year: 2024. https://usatrade.census.gov/