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(1S,2R,5S)-(+)-Menthol

Drug ingredient

CAS 15356-60-2

EPA’s 2023 records show zero U.S. production for this drug ingredient.

Molecular structure of 15356-60-2
US productionZero
Import value, 2024$72M
Import volumeCBI
Top sourceGermany 59%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290611 · narrow

EPA reports by year
2023
US production Zero · Imports Confidential
2019
US production Confidential · Imports Confidential

These shares come from HS customs code 290611, which covers 4 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
DE 59%GermanyIN 35%IndiaSG 3%SingaporeMY 1%MalaysiaCN 1%China
EPA-registered importers (2)
Symrise Ag · DE Germany
Symrise

Why It Matters

Sectors
Core ChemicalsHealth
Downstream Uses

Appears in 11 drug and cosmetic product listings (FDA).

  • •BlueStop Max
  • •Re-Lieved 3 in 1 Patch
  • •Tommie Copper Cooling Roller Lavender Scent
  • •LidoPro Pain Relief
  • •AY Bendito - Thermoactive
  • •AY Bendito - PAIN Relief
  • •PAIN Relief Menthol AND Snake Venom
  • •CVS Pain Relief
Show all 11
  • •Menthol 5%
  • •XRay Pain Relief
  • •Cryomax Cooling
FDA Shortage Status
No FDA shortage records

Industrial Uses

  • •Odor agents in All Other Basic Organic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.12/gSigma-Aldrich (Rush Stock)
CountryGermany
Pack$488.49 / 4 kg
Purity95%
Vendors21 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

20 more vendors
VendorCountry$/gPackPurity
Sigma-AldrichGermany$0.124 kg95%
Combi-Blocks, Inc.United States$0.251 kg97%
AK Scientific SpecializedUnited States$0.29500 g95%
AK Scientific, Inc.United States$0.38500 g99%
Aaron Chemicals LLCHong Kong$0.58100 g97%
Ambeed, Inc.United States$0.62100 g98%
Angene ChemicalChina → Hong Kong$0.69100 g97%
A2B Chem LLCUnited States$0.7625 g98%
AA BLOCKSUnited States$0.8425 g98%
Fluorochem UKUnited Kingdom$12.871 g97%
InterbioscreenHong Kong$34.0010 g95%
MolnovaChina$380.00100 mg99%
TargetMol ChemicalsChina → United States$420.00100 mg99.88%
Apexbio Technology LLCUnited States$425.00200 mg98%
ChemFacesChina$1500.0020 mg98%
Otava, Ltd. (2 weeks)Ukraine$2724.0050 mg90%
Princeton BioMolecular Research (SC)United States$2900.00100 mg90%
Vitas M Chemical LimitedHong Kong$3170.00100 mg90%
AngeneChina → Hong Kong$4266.6730 mg97%
AstaTech (2 weeks)United States$11900.0010 mg95%

Chemical Identity

CAS15356-60-2
PubChem CID165675
DTXSIDDTXSID8029733
FormulaC10H20O
Mol. Weight156.26 g/mol
SMILESCC1CCC(C(C1)O)C(C)C

Data Sources

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Brief citations

(1S,2R,5S)-(+)-Menthol (CAS 15356-60-2) https://chemicalindependence.com/chemical/15356-60-2/ EPA CompTox (DSSTox): DTXSID8029733. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029733 PubChem: 165675. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/165675 EPA Chemical Data Reporting: 15356-60-2. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 15356-60-2. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290611 for CAS 15356-60-2. Reporting year: 2024. https://usatrade.census.gov/