Rutin

Drug ingredient

CAS 153-18-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$7M

Top sourceChina 79%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293810 · narrow

These shares come from HS customs code 293810, which covers 3 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 79%ChinaES 19%SpainBR 2%Brazil

Japan
Canada

6 FDA-registered drug labelers

Advanced Pharmaceutical Services, Inc. Dba Affordable Quality Pharmaceuticals

Deseret Biologicals, Inc.

Dr. Donna Restivo DC

Energique, Inc.

Professional Complementary Health Formulas

Puretek Corporation

Why It Matters

Sectors

Health

Downstream Uses

Appears in 12 drug and cosmetic product listings (FDA).

•Dairy Allergen Mix
•Chip Cravings
•Respiratory Plus
•Bruselix Bruising
•Opsin I 6014
•St. Paul Brands Verestor
•Multi-Phenolic
•Allermilk

Show all 12

•Bio Placenta Phase
•JBA Verestor Mega Fiber Powder
•Grain and Soy Allergen Mix
•Rutin 1541

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS153-18-4

PubChem CID5280805

DTXSIDDTXSID3022326

FormulaC27H30O16

Mol. Weight610.5 g/mol

SMILESCC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O)O)O)O)O)O

Data Sources

PubChem · compound 5280805Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Rutin (CAS 153-18-4) https://chemicalindependence.com/chemical/153-18-4/ PubChem: 5280805. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5280805 EPA TSCA Inventory: CAS 153-18-4. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293810 for CAS 153-18-4. Reporting year: 2024. https://usatrade.census.gov/