leucovorin calcium

Drug ingredient

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 1492-18-8

Where It Comes From

31 FDA-registered drug labelers
American Health Packaging
Avyxa Pharma, LLC
AX Pharmaceutical Corp
BluePoint Laboratories
Cerbios-Pharma SA
Epic Pharma LLC
FARMASIERRA MANUFACTURING SL
Fresenius Kabi USA, LLC
Gland Pharma Limited
GLENMARK PHARMACEUTICALS INC., USA
GMT Fine Chemicals SA
Hikma Pharmaceuticals USA Inc.
Huzhou Zhanwang Pharmaceutical Co., Ltd.
Ingenus Pharmaceuticals, LLC
Leading Pharma, LLC
LETCO MEDICAL, LLC
Major Pharmaceuticals
Meitheal Pharmaceuticals Inc.
MERCK & CIE
MOLCLONE LABS PRIVATE LIMITED
Mylan Institutional LLC
Pfizer Laboratories Div Pfizer Inc
Professional Compounding Centers of America
Professional Compounding Centers of America dba PCCA
Proficient Rx LP
Qingdao Biopeptek Co., Ltd.
Sagent Pharmaceuticals
Slate Run Pharmaceuticals, LLC
Spectrum Laboratory Products, Inc.
Teva Pharmaceuticals USA, Inc.
Willow Birch Pharma, Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

  • leucovorin calcium
  • Vykoura
  • Lederle Leucovorin
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS1492-18-8
PubChem CID135403647
DTXSIDDTXSID20872448
FormulaC20H21CaN7O7
Mol. Weight511.5 g/mol
SMILESC1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Ca+2]

Data Sources

1354036472026-04-07

https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/name/leucovorin calcium/cids/JSON

Archive: data/sources/pubchem_name/leucovorin calcium.json

CAS 1492-18-82026-04-25

https://open.fda.gov/data/ndc/

Archive: data/sources/fda/ndc/ndc.json

bulk match2026-04-07

https://open.fda.gov/data/ndc/

Archive: data/sources/fda/ndc/ndc.json