Flag of the United StatesAmerican Chemical Independence

Melphalan

Drug ingredient

CAS 148-82-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 148-82-3
US productionNot reported
Import value, 2024$503M
Top sourceChina 25%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292249 · basket

These shares come from HS customs code 292249, which covers 170 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 25%ChinaIN 17%IndiaSG 13%SingaporeIT 9%ItalyCH 7%Switzerland
5 FDA-registered drug labelers
American Pacific Corporation
DARMERICA, LLC
Kekule Life Sciences Limited
MAEDA INC
Sionc Pharmaceutical Private Limited

Why It Matters

Sectors
Health
Downstream UsesNot recorded
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS148-82-3
PubChem CID460612
DTXSIDDTXSID6020804
FormulaC13H18Cl2N2O2
Mol. Weight305.2 g/mol
SMILESC1=CC(=CC=C1CC(C(=O)O)N)N(CCCl)CCCl

Data Sources

← Back to Dashboard← Back to Health

Brief citations

Melphalan (CAS 148-82-3) https://chemicalindependence.com/chemical/148-82-3/ PubChem: 460612. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/460612 FDA National Drug Code directory: CAS 148-82-3. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292249 for CAS 148-82-3. Reporting year: 2024. https://usatrade.census.gov/