pilocarpine nitrate

Drug ingredient

CAS 148-72-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$171M

Top sourceSwitzerland 40%

EPA lists this chemical as inactive, meaning no company reported making, importing or processing it in the US from 2006 to 2016.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293979 · basket

These shares come from HS customs code 293979, which covers 60 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CH 40%SwitzerlandCN 18%ChinaIT 14%ItalyDE 13%GermanyIN 10%India

Australia
Poland
Belgium
Taiwan
Canada
Japan
Spain
Mexico
New Zealand
Slovenia
Israel

2 FDA-registered drug labelers

C-SQUARED PHARMA LIMITED

C-squared Pharma Sarl

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$27.53/gSigma-Aldrich (Rush Stock)

CountryGermany

Pack$688.25 / 25 g

Purity98%

Vendors13 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

12 more vendors

Vendor	Country	$/g	Pack	Purity
Sigma-Aldrich	Germany	$27.53	25 g	98%
A2B Chem LLC	United States	$39.40	5 g	99.53%
AA BLOCKS	United States	$42.00	5 g	99.53%
Angene International Limited	United States	$111.60	5 g	98%
TargetMol Chemicals	China → United States	$184.00	500 mg	99.92%
Molnova	China	$370.00	100 mg	99%
Aaron Chemicals LLC	Hong Kong	$409.00	1 g	98%
Angene Chemical	China → Hong Kong	$413.00	1 g	98%
Labotest KG	Germany	$453.00	1000 mg	90%
MedChemExpress MCE	Sweden	$629.20	100 mg	99.87%
TimTec, LLC	United States	$52000.00	5 mg	90%
Interbioscreen	Hong Kong	$145475.00	2 mg	92%

Chemical Identity

CAS148-72-1

PubChem CID657349

DTXSIDDTXSID80883277

FormulaC11H17N3O5

Mol. Weight271.27 g/mol

SMILESCCC1C(COC1=O)CC2=CN=CN2C.[N+](=O)(O)[O-]

Data Sources

PubChem · compound 657349Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

pilocarpine nitrate (CAS 148-72-1) https://chemicalindependence.com/chemical/148-72-1/ PubChem: 657349. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/657349 EPA TSCA Inventory: CAS 148-72-1. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293979 for CAS 148-72-1. Reporting year: 2024. https://usatrade.census.gov/