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Bosentan

Drug ingredient

CAS 147536-97-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 147536-97-8
US productionNot reported
Import value, 2024$2.0B
Top sourceIreland 63%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293590 · basket

These shares come from HS customs code 293590, which covers 182 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 63%IrelandSG 14%SingaporeIN 7%IndiaCN 7%ChinaCH 2%Switzerland
14 FDA-registered drug labelers
Actavis Pharma, Inc.
Actelion Pharmaceuticals US, Inc.
Aurobindo Pharma Limited
Cadila Pharmaceuticals Limited
Cipla Ltd.
Honour Lab Limited
Jubilant Biosys limited
Lupin Pharmaceuticals, Inc.
MSN Laboratories Private Limited
MYLAN LABORATORIES LIMITED
SUN PHARMACEUTICAL INDUSTRIES, INC.
Viyash Life Sciences Private Limited
Zydus Lifesciences Limited
Zydus Pharmaceuticals USA Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

  • •Bosentan
  • •Tracleer
FDA Shortage Status
No Shortage
Shortage History
  • to be discontinued

    Bosentan Tablet

    Shortage listed since June 9, 2025

See all current drug shortages

Vendor Pricing

$39.00/gA2B Chem LLC
CountryUnited States
Pack$195.00 / 5 g
Purity99.84%
Vendors17 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

16 more vendors
VendorCountry$/gPackPurity
Combi-Blocks, Inc.United States$39.005 g98%
AA BLOCKSUnited States$44.805 g95%
AstaTech, IncUnited States$288.001 g95%
MolnovaChina$588.00500 mg99%
TargetMol ChemicalsChina → United States$654.00500 mg99.99%
Apexbio Technology LLCUnited States$715.00200 mg99.92%
AK Scientific SpecializedUnited States$742.00500 mg95%
Fulfilled by MolportLatvia$800.0050 mg99.99%
Ambeed, Inc.United States$800.0050 mg98%
Aaron Chemicals LLCHong Kong$860.00250 mg98%
Angene International LimitedUnited States$888.00250 mg95%
Angene ChemicalChina → Hong Kong$988.00250 mg98%
MedChemExpress MCESweden$989.78500 mg99.98%
AK Scientific, Inc.United States$992.00500 mg98%
Cayman EuropeEstonia$3546.2050 mg98%
MedKoo Biosciences, IncUnited States$4750.00200 mg98%

Chemical Identity

CAS147536-97-8
PubChem CID104865
DTXSIDDTXSID7046627
FormulaC27H29N5O6S
Mol. Weight551.6 g/mol
SMILESCC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4OC

Data Sources

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Brief citations

Bosentan (CAS 147536-97-8) https://chemicalindependence.com/chemical/147536-97-8/ PubChem: 104865. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/104865 FDA National Drug Code directory: CAS 147536-97-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 147536-97-8. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293590 for CAS 147536-97-8. Reporting year: 2024. https://usatrade.census.gov/