omaveloxolone

Drug ingredient

CAS 1474034-05-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$281M

Top sourceChina 31%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292690 · basket

These shares come from HS customs code 292690, which covers 191 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 31%ChinaIT 15%ItalyGB 14%United KingdomIN 11%IndiaJP 8%Japan

South Korea
Spain
Ireland
Ukraine
Malaysia
Brazil
Hong Kong
Latvia
Australia

3 FDA-registered drug labelers

American Pacific Corporation

Biogen

Hovione LLC

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Skyclarys

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS1474034-05-3

PubChem CID71811910

DTXSIDDTXSID101138251

FormulaC33H44F2N2O3

Mol. Weight554.7 g/mol

SMILESCC1(CCC2(CCC3(C(C2C1)C(=O)C=C4C3(CCC5C4(C=C(C(=O)C5(C)C)C#N)C)C)C)NC(=O)C(C)(F)F)C

Data Sources

PubChem · compound 71811910Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

omaveloxolone (CAS 1474034-05-3) https://chemicalindependence.com/chemical/1474034-05-3/ PubChem: 71811910. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/71811910 FDA National Drug Code directory: CAS 1474034-05-3. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292690 for CAS 1474034-05-3. Reporting year: 2024. https://usatrade.census.gov/