L-Proline

Drug ingredient

America imports all of this drug ingredient. EPA records show zero U.S. production.

Molecular structure of 147-85-3
US ProductionZero
Import Value$1.4B
Import Volume46.4K lbs
Import Dependency100%
Top SourceIreland 33%
L-Proline · US import value by year
$4.7B2013$1.4B2025

Where It Comes From

Customs basis: HS 293399 · basket

These shares come from HS customs code 293399, which covers 48 chemicals in total. They estimate the bucket's origin mix, not this chemical specifically.

Source Countries
IE 33%IrelandCN 26%ChinaIN 11%IndiaDE 9%GermanyIT 4%Italy
EPA-registered importers (1)
Ferro

Why It Matters

Sectors
HealthMetals & Mining
Downstream Uses

Appears in 16 drug and cosmetic product listings (FDA).

  • Aminosyn-PF
  • Plenamine
  • Kabiven
  • Clinimix
  • Clinimix E
  • Clinisol
  • ProSol
  • TrophAmine
Show all 16
  • TH-101
  • Aminosyn II
  • Metabatone
  • Vital Skin Hair Nails
  • Travasol
  • Perikabiven
  • Metab
  • Premasol - sulfite-free (Amino Acid)
FDA Shortage Status
No FDA shortage records

Industrial Uses

Used in 1 sector as 1 functional role.

  • Dispersing agent in Miscellaneous ManufacturingProcessing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.09/gAaron Chemicals LLC
CountryHong Kong
Pack$43.00 / 500 g
Purity98%
Vendors30 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

29 more vendors
VendorCountry$/gPackPurity
Angene ChemicalChina Hong Kong$0.091 kg98%
A2B Chem LLCUnited States$0.09500 g98%
AA BLOCKSUnited States$0.11500 g98%
ChemsceneUnited States$0.131 kg
BLD Pharmatech Co., LimitedUnited States$0.141 kg98%
BLD Pharmatech GmbHGermany$0.141 kg98%
BLD Pharmatech Ltd.China$0.141 kg98%
Ambeed, Inc.United States$0.141 kg98%
Fluorochem EUGermany$0.15500 g98%
Fluorochem UKUnited Kingdom$0.15500 g98%
AstaTech, IncUnited States$0.19500 g98%
MedChemExpress MCESweden$0.23500 g98%
AK Scientific SpecializedUnited States$0.251 kg95%
Combi-Blocks, Inc.United States$0.251 kg98%
AK Scientific, Inc.United States$0.351 kg99%
Acrotein ChemBio, Inc.United States$0.42250 g
Manchester OrganicsUnited Kingdom$0.42250 g
Angene International LimitedUnited States$0.49100 g98%
Sigma-Aldrich (Rush Stock)Germany$5.1925 g99%
Sigma-AldrichGermany$5.1925 g99%
MolnovaChina$76.00500 mg99%
Labotest KGGermany$217.805000 mg90%
ChemFacesChina$1500.0020 mg98%
Otava, Ltd.Ukraine$1840.00250 mg95%
Princeton BioMolecular Research (SC)United States$4200.0050 mg90%
AngeneChina Hong Kong$4266.6730 mg98%
Vitas M Chemical LimitedHong Kong$6250.0020 mg90%
Life Chemicals Inc.Ukraine Canada$9900.0010 mg90%
TimTec, LLC (back-ordered)United States$32000.0015 mg94%

Chemical Identity

CAS147-85-3
PubChem CID145742
DTXSIDDTXSID5044021
FormulaC5H9NO2
Mol. Weight115.13 g/mol
SMILESC1CC(NC1)C(=O)O

Data Sources

DTXSID50440212026-04-06

https://doi.org/10.23645/epacomptox.5588566

Archive: data/sources/comptox/dsstox_identifiers.csv

1457422026-04-06

https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/145742/property/MolecularFormula,MolecularWeight,CanonicalSMILES,InChIKey/JSON

Archive: data/sources/pubchem_properties/145742.json

147-85-32026-04-24

https://www.epa.gov/chemical-data-reporting

Archive: data/sources/epa_cdr/2020_cdr.csv

CAS 147-85-32026-04-25

https://www.epa.gov/chemical-data-reporting

Archive: data/sources/epa_cdr/2020_cdr_industrial.csv