Dexmedetomidine hydrochloride
Drug ingredientActive ShortageCAS 145108-58-3
This drug ingredient is in active FDA shortage. At least one manufacturer cannot meet demand.
This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.
Why supply is unknownWhere It Comes From
EPA and Census publish no US supply data for this chemical.
40 FDA-registered drug labelers
Why It Matters
Appears in 7 drug and cosmetic product listings (FDA).
- •Precedex
- •Dexmedetomidine Hydrochloride
- •Dexmedetomidine Hydrochloride in 0.9% Sodium Chloride
- •Dexmedetomidine HCl
- •Dexmedetomidine
- •Dexmedetomidine in Dextrose
- •Dexmedetomidine Hydrochloride in Sodium Chloride
- Current shortage
Dexmedetomidine Hydrochloride Injection
Shortage listed since April 10, 2020
Manufacturer reports: 1 unavailable, 1 limited, 2 available
Vendor Pricing
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
12 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| Angene Chemical | China → Hong Kong | $24.80 | 5 g | 99% |
| Combi-Blocks, Inc. | United States | $25.60 | 25 g | 98% |
| AA BLOCKS | United States | $36.30 | 10 g | 99.96% |
| AK Scientific Specialized | United States | $119.00 | 5 g | 95% |
| AK Scientific, Inc. | United States | $169.60 | 5 g | 98% |
| MedKoo Biosciences, Inc | United States | $250.00 | 5 g | 98% |
| A2B Chem LLC | United States | $370.00 | 100 mg | 98% |
| TargetMol Chemicals | China → United States | $510.00 | 500 mg | 99.96% |
| Angene | China → Hong Kong | $4266.67 | 30 mg | 99% |
| Axon Medchem | Netherlands | $4320.00 | 50 mg | 99% |
| Key Organics Ltd. | United Kingdom | $6900.00 | 10 mg | 99% |
| Angene International Limited | United States | $8240.00 | 100 mg | 99% |
Chemical Identity
Data Sources
- PubChem · compound 6918081Retrieved 2026-04-07
- FDA National Drug Code directoryRetrieved 2026-04-25
- FDA Drug ShortagesRetrieved 2026-10-04
Brief citations
Dexmedetomidine hydrochloride (CAS 145108-58-3) https://chemicalindependence.com/chemical/145108-58-3/ PubChem: 6918081. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/6918081 FDA National Drug Code directory: CAS 145108-58-3. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 145108-58-3. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/