Flag of the United StatesAmerican Chemical Independence

Pregnenolone

Drug ingredient

CAS 145-13-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 145-13-1
US productionNot reported
Import value, 2024$154M
Top sourceItaly 60%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293729 · basket

These shares come from HS customs code 293729, which covers 57 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IT 60%ItalyES 14%SpainCN 11%ChinaDE 6%GermanyAT 2%Austria
11 FDA-registered drug labelers
BioActive Nutritional, Inc.
BioActive Nutritionals, Inc.
BLA Enterprises, LLC
Hubei Gedian Humanwell Pharmaceutical Co., Ltd.
Hubei Zhuxi Humanwell Pharmaceutical Co., Ltd.
Jiangsu Jiaerke Pharmaceuticals Group Corp., Ltd.
Kalchem International inc
Medisca Inc.
Pharma Source Direct, Inc.
Professional Complementary Health Formulas
Professional Compounding Centers of America dba PCCA

Why It Matters

Sectors
Health
Downstream Uses

Appears in 6 drug and cosmetic product listings (FDA).

  • •DHEA Forte
  • •Immune Forte
  • •Gynobalance
  • •Kidney/Prostate/Adrenal Drops 5011
  • •Kidney/Ovarian/Adrenal Drops 5010
  • •Androbalance
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS145-13-1
PubChem CID8955
DTXSIDDTXSID1036541
FormulaC21H32O2
Mol. Weight316.5 g/mol
SMILESCC(=O)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C

Data Sources

← Back to Dashboard← Back to Health

Brief citations

Pregnenolone (CAS 145-13-1) https://chemicalindependence.com/chemical/145-13-1/ PubChem: 8955. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/8955 FDA National Drug Code directory: CAS 145-13-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293729 for CAS 145-13-1. Reporting year: 2024. https://usatrade.census.gov/