Voxelotor

Drug ingredient

CAS 1446321-46-5

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$1.3B

Top sourceChina 32%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293339 · basket

These shares come from HS customs code 293339, which covers 397 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 32%ChinaIN 15%IndiaDE 10%GermanyBE 9%BelgiumCH 8%Switzerland

Taiwan
Ukraine
Sweden
Argentina
Canada
Finland
Malta
Israel
Netherlands
Denmark
United Arab Emirates
Mexico
Brunei
Slovakia
Australia
South Africa
Poland
Latvia
Lithuania
Estonia
Slovenia
Czech Republic
Croatia
Hong Kong

7 FDA-registered drug labelers

Cambrex Charles City, Inc

Catalent Pharma Solutions, LLC

Esteve Quimica SA

Global Blood Therapeutics, Inc, A subsidiary of Pfizer Inc.

MSN Life Sciences Private Limited

Neuland Laboratories Limited

Patheon Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Oxbryta

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$290.00/gCombi-Blocks, Inc.

CountryUnited States

Pack$1450.00 / 5 g

Purity98%

Vendors19 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

18 more vendors

Vendor	Country	$/g	Pack	Purity
A2B Chem LLC	United States	$306.80	5 g	98%
AA BLOCKS	United States	$323.80	5 g	98%
Angene Chemical	China → Hong Kong	$331.00	1 g	98%
BLD Pharmatech Co., Limited	United States	$480.00	1 g	98%
BLD Pharmatech GmbH	Germany	$480.00	1 g	98%
BLD Pharmatech Ltd.	China	$480.00	1 g	98%
Ambeed, Inc.	United States	$480.00	1 g	98%
Aaron Chemicals LLC	Hong Kong	$491.00	1 g	98%
Excenen Pharmatech Co., Ltd	China	$1500.00	1 g	98%
Molnova	China	$2470.00	200 mg	99%
TargetMol Chemicals	China → United States	$2745.00	200 mg	99.94%
MedChemExpress MCE	Sweden	$2874.96	500 mg	99.99%
AstaTech, Inc	United States	$3192.00	250 mg	95%
TargetMol Chemicals EU	Austria	$3690.00	100 mg	99.94%
TargetMol Chemicals US	United States	$3960.00	50 mg	99.94%
Axon Medchem	Netherlands	$5280.00	50 mg	99%
Angene International Limited	United States	$8330.00	100 mg	95%
Cayman Europe	Estonia	$13042.40	25 mg	98%

Chemical Identity

CAS1446321-46-5

PubChem CID71602803

DTXSIDDTXSID801027954

FormulaC19H19N3O3

Mol. Weight337.4 g/mol

SMILESCC(C)N1C(=CC=N1)C2=C(C=CC=N2)COC3=CC=CC(=C3C=O)O

Data Sources

PubChem · compound 71602803Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

← Back to Dashboard ← Back to Health

Brief citations

Voxelotor (CAS 1446321-46-5) https://chemicalindependence.com/chemical/1446321-46-5/ PubChem: 71602803. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/71602803 FDA National Drug Code directory: CAS 1446321-46-5. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293339 for CAS 1446321-46-5. Reporting year: 2024. https://usatrade.census.gov/