Ripretinib

Drug ingredient

CAS 1442472-39-0

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$907M

Top sourceIreland 47%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293379 · basket

These shares come from HS customs code 293379, which covers 105 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 47%IrelandBE 19%BelgiumSG 11%SingaporeIT 4%ItalyCH 4%Switzerland

Brazil
Canada
Taiwan
Ukraine
Portugal
Netherlands
South Korea
Israel
Czech Republic
Spain
Finland
Hungary
Malaysia
Australia
Austria
Slovenia

2 FDA-registered drug labelers

Cambrex Charles City, Inc

Deciphera Pharmaceuticals, LLC

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Qinlock

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$430.00/gCombi-Blocks, Inc.

CountryUnited States

Pack$430.00 / 1 g

Purity95%

Vendors18 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

17 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$443.60	5 g	98%
Aaron Chemicals LLC	Hong Kong	$485.00	1 g	98%
BLD Pharmatech Ltd.	China	$508.00	1 g	98%
BLD Pharmatech GmbH	Germany	$1250.00	100 mg	98%
Ambeed, Inc.	United States	$1660.00	50 mg	98%
AA BLOCKS	United States	$1880.00	25 mg	98%
BLD Pharmatech Co., Limited	United States	$2360.00	25 mg	98%
A2B Chem LLC	United States	$2400.00	10 mg	98%
Molnova	China	$3564.00	500 mg	99%
MedKoo Biosciences, Inc	United States	$3650.00	1 g	98%
Excenen Pharmatech Co., Ltd	China	$5400.00	250 mg	98%
TargetMol Chemicals	China → United States	$9570.00	100 mg	99.72%
TargetMol Chemicals US	United States	$13660.00	50 mg	99.72%
MedChemExpress MCE	Sweden	$14435.30	100 mg	98.9%
Cayman Europe	Estonia	$16255.40	50 mg	95%
Angene International Limited	United States	$23090.00	100 mg	98%
AstaTech (2 weeks)	United States	$28200.00	100 mg	98%

Chemical Identity

CAS1442472-39-0

PubChem CID71584930

DTXSIDDTXSID201027956

FormulaC24H21BrFN5O2

Mol. Weight510.4 g/mol

SMILESCCN1C2=CC(=NC=C2C=C(C1=O)C3=CC(=C(C=C3Br)F)NC(=O)NC4=CC=CC=C4)NC

Data Sources

PubChem · compound 71584930Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

← Back to Dashboard ← Back to Health

Brief citations

Ripretinib (CAS 1442472-39-0) https://chemicalindependence.com/chemical/1442472-39-0/ PubChem: 71584930. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/71584930 FDA National Drug Code directory: CAS 1442472-39-0. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293379 for CAS 1442472-39-0. Reporting year: 2024. https://usatrade.census.gov/