Disodium hydrogen citrate

CAS 144-33-2

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$130M

Import volumeZero

Top sourceIsrael 39%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291815 · basket

EPA reports by year

2023: US production Confidential · Imports Zero
2019: US production 6.4K lb · Imports Zero

These shares come from HS customs code 291815, which covers 34 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IL 39%IsraelIN 14%IndiaDE 13%GermanyCN 10%ChinaIT 6%Italy

Brazil
Japan
Netherlands
Australia
Lithuania
United Kingdom
Norway
South Korea
Czech Republic
Lebanon
Ireland
Turkey
Estonia
Mexico
Switzerland

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Dystar

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Evonik

Why It Matters

Sectors

Textiles

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in Textiles, apparel, and leather manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Chemical Identity

CAS144-33-2

PubChem CID8950

DTXSIDDTXSID50889423

FormulaC6H6Na2O7

Mol. Weight236.09 g/mol

SMILESC(C(=O)[O-])C(CC(=O)[O-])(C(=O)O)O.[Na+].[Na+]

Data Sources

EPA CompTox (DSSTox) · DTXSID50889423Retrieved 2026-04-06
PubChem · compound 8950Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Disodium hydrogen citrate (CAS 144-33-2) https://chemicalindependence.com/chemical/144-33-2/ EPA CompTox (DSSTox): DTXSID50889423. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID50889423 PubChem: 8950. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/8950 EPA Chemical Data Reporting: 144-33-2. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 144-33-2. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 291815 for CAS 144-33-2. Reporting year: 2024. https://usatrade.census.gov/