piperazine citrate

Drug ingredient

CAS 144-29-6

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$7.6B

Top sourceIreland 61%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293359 · basket

These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India

Israel
Bulgaria
Japan
Spain
Sweden
Canada
Taiwan
Finland
Portugal
Mexico
Belgium
Hungary
Austria
Brazil
Ukraine
Croatia
Malta
South Korea
South Africa
Denmark
Czech Republic
Malaysia
Argentina
Poland
Cameroon
Australia
Hong Kong
Slovakia
Latvia

1 FDA-registered drug labeler

Adani Pharmachem Pvt Ltd

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$0.14/gAK Scientific, Inc.

CountryUnited States

Pack$70.00 / 500 g

Purity98%

Vendors5 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

4 more vendors

Vendor	Country	$/g	Pack	Purity
Combi-Blocks, Inc.	United States	$0.25	1 kg	95%
MedKoo Biosciences, Inc	United States	$18.00	25 g	98%
Molnova	China	$74.00	500 mg	99%
MedChemExpress MCE	Sweden	$75.02	500 mg	98%

Chemical Identity

CAS144-29-6

PubChem CID15595021

DTXSIDDTXSID40883334

FormulaC24H46N6O14

Mol. Weight642.7 g/mol

SMILESC1CNCCN1.C1CNCCN1.C1CNCCN1.C(C(=O)O)C(CC(=O)O)(C(=O)O)O.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

Data Sources

PubChem · compound 15595021Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

piperazine citrate (CAS 144-29-6) https://chemicalindependence.com/chemical/144-29-6/ PubChem: 15595021. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/15595021 EPA TSCA Inventory: CAS 144-29-6. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293359 for CAS 144-29-6. Reporting year: 2024. https://usatrade.census.gov/