ketoconazole

Drug ingredient

CAS 142128-57-2

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 142128-57-2
US productionNot reported
Import value, 2024$6.4B
Top sourceSingapore 36%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293499 · basket

These shares come from HS customs code 293499, which covers 575 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
SG 36%SingaporeIE 23%IrelandCN 11%ChinaCH 6%SwitzerlandIN 5%India
60 FDA-registered drug labelers
A-S Medication Solutions
Amici Pharma Inc.
ANI Pharmaceuticals, Inc.
ASCLEMED USA INC.
Bryant Ranch Prepack
Burel Pharmaceuticals, LLC
Changsha Beiliang E-commerce Co., Ltd
Cosette Pharmaceuticals, Inc.
dandRX LLC
Derivados Quimicos
Direct Rx
E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC
Encube Ethicals, Inc.
Esjay Pharma LLC
Fagron Inc
Golden State Medical Supply, Inc.
Guangdong Quadrant Ecological Technology Co., Ltd.
Guangzhou ChuanMa International Trading Co.,Ltd.
Jiangsu Chenpai Bond Pharmaceutical Co.,Ltd.
KALCHEM INTERNATIONAL INC
Kramer Laboratories
LETCO MEDICAL, LLC
Medimetriks Pharmaceuticals, Inc.
Medisca Inc.
MONTAGE CHEMICALS PRIVATE LIMITED
Nanjing White Whale Pharmaceutical Co., Ltd
NORTHSTAR RX LLC
NuCare Pharmaceuticals,Inc.
NURAY CHEMICALS PRIVATE LIMITED
Padagis Israel Pharmaceuticals Ltd
PD-Rx Pharmaceuticals, Inc.
Piramal Pharma Limited
Preferred Pharmaceuticals Inc.
Professional Compounding Centers of America
Professional Compounding Centers of America dba PCCA
Proficient Rx LP
Quimica Sintetica S.A.
REMEDYREPACK INC.
Sharon Bio-Medicine Limited
Shenzhen Ishan Technology Co., Ltd
Shenzhen Mengyue Technology Co., Ltd.
Spectrum Laboratory Products, Inc.
Sportpharm LLC
STHREE CHEMICALS PRIVATE LIMITED
Strides Pharma Science Limited
Sun Pharmaceutical Industries, Inc.
TAGRID LLC
Teva Pharmaceuticals USA, Inc.
THIRTY MADISON INC
TOLMAR Inc.
Trillium Health Care Products Inc.
Unilab Chemicals and Pharmaceuticals Private Limited
UNION QUIMICO FARMACEUTICA SA
UQUIFA Mexico, S.A. DE C.V.
Viona Pharmaceuticals Inc
Willow Birch Pharma, LLC
Xenex Laboratories Inc
Xiromed, LLC
Yunnan Yuyao Bio-pharmaceutical Co.,Ltd.
Zydus Lifesciences Limited

Why It Matters

Sectors
Health
Downstream Uses

Appears in 15 drug and cosmetic product listings (FDA).

  • •Ketoconazole
  • •Tagrit Antifungal Treament Ketoconazole 1%
  • •Anti Dandruff
  • •Anti-Fungal
  • •Ketoconazole Cream
  • •Danil
  • •1% ketoconazole
  • •Ketodan
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$0.39/gAaron Chemicals LLC
CountryHong Kong
Pack$196.00 / 500 g
Purity98%
Vendors27 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS142128-57-2
PubChem CID47576
DTXSIDDTXSID60161949
FormulaC26H28Cl2N4O4
Mol. Weight531.4 g/mol
SMILESCC(=O)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl

Data Sources

Brief citations

ketoconazole (CAS 142128-57-2) https://chemicalindependence.com/chemical/142128-57-2/ PubChem: 47576. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/47576 FDA National Drug Code directory: CAS 142128-57-2. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293499 for CAS 142128-57-2. Reporting year: 2024. https://usatrade.census.gov/