Vitamin D

Drug ingredient

CAS 1406-16-2

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$295M

Top sourceChina 56%

EPA lists this chemical as inactive, meaning no company reported making, importing or processing it in the US from 2006 to 2016.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293629 · basket

These shares come from HS customs code 293629, which covers 17 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 56%ChinaCH 12%SwitzerlandIN 12%IndiaIT 11%ItalyJP 2%Japan

Spain
Netherlands
Czech Republic
Israel
Guyana
Norway
Australia
Taiwan
Ivory Coast
Honduras
South Korea
Austria
Colombia
Brazil
Mexico
Belgium
South Africa
Turkey
Hong Kong
Chile
Slovenia
Ecuador
Sweden
Vietnam

10 FDA-registered drug labelers

Apex Energetics Inc.

Bryant Ranch Prepack

Exeltis USA, Inc.

Medisca

METHOD PHARMACEUTICALS, LLC

Mission Pharmacal Company

Oncora Pharma, LLC

Professional Complementary Health Formulas

PureTek Corporation

REMEDYREPACK INC.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 15 drug and cosmetic product listings (FDA).

•Tri-Vite Drops with Fluoride
•Multivitamin with Fluoride
•Folixate
•Vitafol One
•M-Natal Plus
•Foltrexyl
•C08 Calcium Metabolism
•Folditam

Show all 15

•Bone Stim Liquescence 3005
•CitraNatal 90 DHA
•Foltamin
•Foltira
•DermacinRx Purefoltin
•Dotremin
•Folixapure

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS1406-16-2

PubChem CIDNot recorded

DTXSIDDTXSID1026295

FormulaNot recorded

Mol. WeightNot recorded

SMILESNot recorded

Data Sources

EPA CompTox (DSSTox) · DTXSID1026295Retrieved 2026-04-29
EPA TSCA InventoryRetrieved 2026-10-04
FDA National Drug Code directoryRetrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Vitamin D (CAS 1406-16-2) https://chemicalindependence.com/chemical/1406-16-2/ EPA CompTox (DSSTox): 1406-16-2. Retrieved 2026-04-29. https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026295 EPA TSCA Inventory: CAS 1406-16-2. Retrieved 2026-10-04. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: CAS 1406-16-2. Retrieved 2026-10-04. https://open.fda.gov/data/ndc/ US Census international trade: HS 293629 for CAS 1406-16-2. Reporting year: 2024. https://usatrade.census.gov/