Sildenafil

Drug ingredient

CAS 139755-83-2

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$2.0B

Top sourceIreland 63%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293590 · basket

These shares come from HS customs code 293590, which covers 182 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 63%IrelandSG 14%SingaporeIN 7%IndiaCN 7%ChinaCH 2%Switzerland

Portugal
Spain
Italy
Austria
Israel
Hungary
Canada
South Korea
Netherlands
Finland
Poland
Indonesia
Ukraine
Mexico
South Africa
Croatia
Greece
Taiwan
Hong Kong

1 FDA-registered drug labeler

Amneal Pharmaceuticals NY LLC

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Sildenafil

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$40.00/gAaron Chemicals LLC

CountryHong Kong

Pack$200.00 / 5 g

Purity95%

Vendors13 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

12 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$46.20	5 g	95%
Fluorochem UK	United Kingdom	$62.92	1 g	97%
Combi-Blocks, Inc.	United States	$96.00	5 g	98%
A2B Chem LLC	United States	$103.80	10 g	98%
AA BLOCKS	United States	$109.60	10 g	98%
MedChemExpress MCE	Sweden	$231.23	10 g	99.99%
AK Scientific Specialized	United States	$418.00	1 g	95%
AK Scientific, Inc.	United States	$587.00	1 g	98%
Angene International Limited	United States	$677.00	1 g	95%
Fulfilled by Molport	Latvia	$800.00	25 mg	95%
Life Chemicals Inc.	Ukraine → Canada	$3100.00	100 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	95%

Chemical Identity

CAS139755-83-2

PubChem CID135398744

DTXSIDDTXSID6023579

FormulaC22H30N6O4S

Mol. Weight474.6 g/mol

SMILESCCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C

Data Sources

PubChem · compound 135398744Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Sildenafil (CAS 139755-83-2) https://chemicalindependence.com/chemical/139755-83-2/ PubChem: 135398744. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/135398744 FDA National Drug Code directory: CAS 139755-83-2. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293590 for CAS 139755-83-2. Reporting year: 2024. https://usatrade.census.gov/