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Ethylenediaminetetraacetic acid, disodium salt

CAS 139-33-3

U.S. production volumes are classified as confidential business information.

Molecular structure of 139-33-3
US productionCBI
Import value, 2024$503M
Top sourceChina 25%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292249 · basket

EPA reports by year
2023
US production Confidential · Imports Confidential
2019
US production Confidential · Imports Confidential

These shares come from HS customs code 292249, which covers 170 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 25%ChinaIN 17%IndiaSG 13%SingaporeIT 9%ItalyCH 7%Switzerland
EPA-registered manufacturers (1)
Dow Chemical
EPA-registered importers (2)
Basf Se · DE Germany
Basf

Why It Matters

Sectors
HealthConsumer ProductsCore Chemicals
Downstream UsesNot recorded
FDA Shortage Status
No FDA shortage records

Industrial Uses

Used in 4 sectors as 3 functional roles.

  • •Ion exchange agent in All Other Basic Organic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •CBI in CBICBI
  • •Chelating agent in Pharmaceutical and Medicine Manufacturing (30%)Processing—repackaging
  • •Chelating agent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (70%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.01/gAaron Chemicals LLC
CountryHong Kong
Pack$9.00 / 1 kg
Purity99.5%
Vendors24 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

23 more vendors
VendorCountry$/gPackPurity
Angene ChemicalChina → Hong Kong$0.011 kg99.5%
A2B Chem LLCUnited States$0.021 kg98%
AA BLOCKSUnited States$0.021 kg98%
BLD Pharmatech Co., LimitedUnited States$0.031 kg98%
BLD Pharmatech GmbHGermany$0.031 kg98%
BLD Pharmatech Ltd.China$0.031 kg98%
Ambeed, Inc.United States$0.031 kg98%
ChemsceneUnited States$0.051 kg—
Angene International LimitedUnited States$0.06500 g98%
Fluorochem EUGermany$0.061 kg98%
Apollo Scientific USUnited Kingdom$0.071 kg99%
Sigma-Aldrich (Rush Stock)Germany$0.075 kg98.5%
Sigma-AldrichGermany$0.075 kg98.5%
AK Scientific, Inc.United States$0.091 kg99%
Fluorochem UKUnited Kingdom$0.10100 g98%
MedChemExpress MCESweden$43.561 g98%
Apexbio Technology LLCUnited States$55.001 g98%
MolnovaChina$70.001 g99%
Labotest KGGermany$453.001000 mg90%
Princeton BioMolecular Research (SC)United States$2900.00100 mg90%
Vitas M Chemical LimitedHong Kong$3170.00100 mg90%
AngeneChina → Hong Kong$4266.6730 mg99.5%
TimTec, LLCUnited States$9333.3330 mg99.995%

Chemical Identity

CAS139-33-3
PubChem CID6049
DTXSIDDTXSID9027073
FormulaC10H16N2O8
Mol. Weight292.24 g/mol
SMILESC(CN(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O

Data Sources

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Brief citations

Ethylenediaminetetraacetic acid, disodium salt (CAS 139-33-3) https://chemicalindependence.com/chemical/139-33-3/ EPA CompTox (DSSTox): DTXSID9027073. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID9027073 PubChem: 6049. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6049 EPA Chemical Data Reporting: 139-33-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 139-33-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292249 for CAS 139-33-3. Reporting year: 2024. https://usatrade.census.gov/