Eszopiclone

Drug ingredient

CAS 138729-47-2

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$907M

Top sourceIreland 47%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293379 · basket

These shares come from HS customs code 293379, which covers 105 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 47%IrelandBE 19%BelgiumSG 11%SingaporeIT 4%ItalyCH 4%Switzerland

Brazil
Canada
Taiwan
Ukraine
Portugal
Netherlands
South Korea
Israel
Czech Republic
Spain
Finland
Hungary
Malaysia
Australia
Austria
Slovenia

37 FDA-registered drug labelers

A-S Medication Solutions

Advanced Rx of Tennessee, LLC

Advanced Rx Pharmacy of Tennessee, LLC

Alivus Life Sciences Limited

Aphena Pharma Solutions - Tennessee, LLC

Asclemed USA, Inc.

Aurobindo Pharma Limited

AURORE PHARMACEUTICALS PRIVATE LIMITED

Bionpharma Inc.

Bryant Ranch Prepack

Calyx Chemicals & Pharmaceuticals Limited

Camber Pharmaceuticals, Inc.

Chromo Laboratories India Private Limited

DIRECT RX

Dr. Reddy's Laboratories Limited

Emcure Pharmaceuticals Limited

Farmak, a,s

Glenmark Pharmaceuticals Inc. USA

Golden State Medical Supply, Inc.

Lake Erie Medical DBA Quality Care Products LLC

Lupin Pharmaceuticals, Inc.

Macleods Pharmaceuticals Limited

Matrix Pharmacorp Private Limited

Mylan Pharmaceuticals Inc.

NuCarePharmaceuticals, Inc.

Patheon Inc.

PD-Rx Pharmaceuticals, Inc.

Preferred Pharmaceuticals Inc.

Proficient Rx LP

Quality Care Products LLC

REMEDYREPACK INC.

St Mary's Medical Park Phcy

Sun Pharmaceutical Industries, Inc.

Symed Labs Limited

TAPI Croatia Industries Ltd.

Teva Pharmaceuticals USA, Inc.

Waylis Therapeutics LLC

Why It Matters

Sectors

Health

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•Eszopiclone
•Lunesta

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No Shortage

Shortage History

Rows group FDA shortage filings by drug product. Each manufacturer makes its own FDA shortage filing, so one product can carry several reports at once: Available, Limited Availability, Unavailable or to be discontinued.

to be discontinued
Eszopiclone Tablet
Shortage listed since June 26, 2025

See all current drug shortages

Chemical Identity

CAS138729-47-2

PubChem CID969472

DTXSIDDTXSID8046086

FormulaC17H17ClN6O3

Mol. Weight388.8 g/mol

SMILESCN1CCN(CC1)C(=O)OC2C3=NC=CN=C3C(=O)N2C4=NC=C(C=C4)Cl

Data Sources

PubChem · compound 969472Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA Drug ShortagesRetrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

← Back to Dashboard ← Back to Health

Brief citations

Eszopiclone (CAS 138729-47-2) https://chemicalindependence.com/chemical/138729-47-2/ PubChem: 969472. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/969472 FDA National Drug Code directory: CAS 138729-47-2. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 138729-47-2. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293379 for CAS 138729-47-2. Reporting year: 2024. https://usatrade.census.gov/