cobamamide

Drug ingredient

CAS 13870-90-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 13870-90-1 — 1 Co³⁺

US productionNot reported

Import value, 2024$70M

Top sourceChina 85%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293626 · narrow

These shares come from HS customs code 293626, which covers 4 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 85%ChinaES 9%SpainIN 3%IndiaIT 2%ItalyPT 1%Portugal

Mexico
Germany
Colombia
Canada
Poland
United Kingdom
South Korea
Turkey
Estonia

2 FDA-registered drug labelers

Jaymac Pharmaceuticals

Jaymac Pharmaceuticals, LLC

Why It Matters

Sectors

Health

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•EnBrace HR
•PaxLyte

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS13870-90-1

PubChem CID6436143

DTXSIDDTXSID1046009

FormulaC72H100CoN18O17P

Mol. Weight1579.6 g/mol

SMILESCC1=CC2=C(C=C1C)N(C=N2)C3C(C(C(O3)CO)OP(=O)([O-])OC(C)CNC(=O)CCC4(C(C5C6(C(C(C(=N6)C(=C7C(C(C(=N7)C=C8C(C(C(=N8)C(=C4[N-]5)C)CCC(=O)N)(C)C)CCC(=O)N)(C)CC(=O)N)C)CCC(=O)N)(C)CC(=O)N)C)CC(=O)N)C)O.[CH2-]C1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O.[Co+3]

Data Sources

PubChem · compound 6436143Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

cobamamide (CAS 13870-90-1) https://chemicalindependence.com/chemical/13870-90-1/ PubChem: 6436143. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/6436143 FDA National Drug Code directory: CAS 13870-90-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293626 for CAS 13870-90-1. Reporting year: 2024. https://usatrade.census.gov/