pemetrexed
Drug ingredientThis chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.
Where It Comes From
5 FDA-registered drug labelers
Avyxa Pharma, LLC
Jiangsu Hansoh Pharmaceutical Group Co., Ltd.
MSN Laboratories Private Limited
ScinoPharm Taiwan Ltd.
Teva Czech Industries s.r.o
Why It Matters
Sectors
Health
Downstream Uses
Appears in 2 drug and cosmetic product listings (FDA).
- •Axtle
- •Pemetrexed Dipotassium
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No Shortage
Shortage History
Each row is a separate manufacturer's FDA shortage filing — not a timeline for the drug as a whole. Multiple "current" entries are normal: each manufacturer/NDC files independently. Status reflects the manufacturer's report; reason describes their supply situation (Available, Unavailable, or to be discontinued).
to be discontinued
Pemetrexed Disodium Injection
10/10/2025to be discontinued
Pemetrexed Ditromethamine Injection
07/17/2025to be discontinued
Pemetrexed Disodium Injection
10/16/2025Chemical Identity
CAS137281-23-3
PubChem CID135410875
DTXSIDDTXSID2048329
FormulaC20H21N5O6
Mol. Weight427.4 g/mol
SMILESC1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)NC(CCC(=O)O)C(=O)O
Data Sources
1354108752026-04-07
https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/name/pemetrexed/cids/JSON
Archive: data/sources/pubchem_name/pemetrexed.json
CAS 137281-23-32026-04-25
https://open.fda.gov/data/ndc/
Archive: data/sources/fda/ndc/ndc.json
CAS 137281-23-32026-06-13
https://api.fda.gov/drug/shortages.json
Archive: data/sources/fda/shortages/shortages.json