4,4'-Methylenebis(2,6-diethylaniline)

CAS 13680-35-8

Companies reported imports and no US production of this chemical to EPA for 2023.

US productionZero

Import value, 2024$84M

Import volume55.7K lb

Import dependency100%

Top sourceJapan 31%

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

4,4'-Methylenebis(2,6-diethylaniline) · US import value by year

2013: $115M · Peak 2022: $148M · 2024: $84M · 2025: $96M

Where It Comes From

Customs basis: HS 292159 · basket

EPA reports by year

2023: US production Zero · Imports 55.7K lb
2019: US production Zero · Imports 58.4K lb

These shares come from HS customs code 292159, which covers 51 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

JP 31%JapanIN 26%IndiaCN 21%ChinaCH 13%SwitzerlandBE 4%Belgium

United Kingdom
South Korea
Canada
Italy
Ukraine
Netherlands

EPA-registered importers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Arxada

Why It Matters

Sectors

Paints & Coatings

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Hardener in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.04/gA2B Chem LLC

CountryUnited States

Pack$38.00 / 1 kg

Purity98%

Vendors19 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

18 more vendors

Vendor	Country	$/g	Pack	Purity
AA BLOCKS	United States	$0.05	1 kg	98%
Aaron Chemicals LLC	Hong Kong	$0.05	500 g	98%
Chemscene	United States	$0.05	1 kg	—
Ambeed, Inc.	United States	$0.05	1 kg	98%
Angene Chemical	China → Hong Kong	$0.05	500 g	98%
BLD Pharmatech GmbH	Germany	$0.06	1 kg	98%
BLD Pharmatech Ltd.	China	$0.06	1 kg	98%
Fluorochem EU	Germany	$0.06	1 kg	98%
MedChemExpress MCE	Sweden	$0.07	1 kg	—
BLD Pharmatech Co., Limited	United States	$0.22	100 g	98%
Combi-Blocks, Inc.	United States	$0.30	500 g	98%
AK Scientific, Inc.	United States	$0.42	100 g	98%
Angene International Limited	United States	$1.00	100 g	98%
Sigma-Aldrich (Rush Stock)	Germany	$1.17	100 g	99%
Sigma-Aldrich	Germany	$1.17	100 g	99%
AstaTech (2 weeks)	United States	$3.08	25 g	95%
Labotest KG	Germany	$217.80	5000 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	98%

Chemical Identity

CAS13680-35-8

PubChem CID83656

DTXSIDDTXSID4048191

FormulaC21H30N2

Mol. Weight310.5 g/mol

SMILESCCC1=CC(=CC(=C1N)CC)CC2=CC(=C(C(=C2)CC)N)CC

Data Sources

EPA CompTox (DSSTox) · DTXSID4048191Retrieved 2026-04-06
PubChem · compound 83656Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

4,4'-Methylenebis(2,6-diethylaniline) (CAS 13680-35-8) https://chemicalindependence.com/chemical/13680-35-8/ EPA CompTox (DSSTox): DTXSID4048191. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID4048191 PubChem: 83656. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/83656 EPA Chemical Data Reporting: 13680-35-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 13680-35-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292159 for CAS 13680-35-8. Reporting year: 2024. https://usatrade.census.gov/