palonosetron hydrochloride
Drug ingredientThis chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.
Where It Comes From
29 FDA-registered drug labelers
Apotex Corp.
Aurobindo Pharma Limited
Avenacy, Inc.
Avyxa Pharma, LLC
Baxter Healthcare Corporation
BluePoint Laboratories
Catalent Pharma Solutions, LLC
Cipla Ltd.
Cipla USA Inc.
Dr.Reddy's Laboratories Limited
Emcure Pharmaceuticals Limited
Eugia US LLC
Fresenius Kabi USA, LLC
HAS Healthcare Advanced Synthesis SA
Helsinn Therapeutics (U.S.), Inc.
Meitheal Pharmaceuticals Inc.
MSN Laboratories Private Limited
Mylan Institutional LLC
NorthStar Rx LLC
Qilu Pharmaceutical Co. Ltd.
Rolabo Outsourcing S.L.
Sagent Pharmaceuticals
Sandoz Inc
TAPI Czech Industries s.r.o.
Teva Czech Industries s.r.o
Teva Parenteral Medicines, Inc.
TYCHE INDUSTRIES LIMITED
USV Private Limited
Wavelength Enterprises LTD
Why It Matters
Sectors
Health
Downstream Uses
Appears in 4 drug and cosmetic product listings (FDA).
- •Palonosetron
- •posfrea
- •Palonosetron Hydrochloride
- •Akynzeo
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No Shortage
Shortage History
Each row is a separate manufacturer's FDA shortage filing — not a timeline for the drug as a whole. Multiple "current" entries are normal: each manufacturer/NDC files independently. Status reflects the manufacturer's report; reason describes their supply situation (Available, Unavailable, or to be discontinued).
to be discontinued
Palonosetron Hydrochloride Injection
11/14/2025Chemical Identity
CAS135729-62-3
PubChem CID6918303
DTXSIDDTXSID8046610
FormulaC19H25ClN2O
Mol. Weight332.9 g/mol
SMILESC1CC2CN(C(=O)C3=CC=CC(=C23)C1)C4CN5CCC4CC5.Cl
Data Sources
69183032026-04-07
https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/name/palonosetron hydrochloride/cids/JSON
Archive: data/sources/pubchem_name/palonosetron hydrochloride.json
CAS 135729-62-32026-04-25
https://open.fda.gov/data/ndc/
Archive: data/sources/fda/ndc/ndc.json
CAS 135729-62-32026-06-13
https://api.fda.gov/drug/shortages.json
Archive: data/sources/fda/shortages/shortages.json