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Calcium silicate

Drug ingredient

CAS 1344-95-2

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

Molecular structure of 1344-95-2
1 Ca²⁺
US productionCBI
Import value, 2024$21M
Top sourceMexico 25%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 283990 · basket

EPA reports by year
2023
US production Confidential · Imports Confidential
2019
US production Confidential · Imports Confidential

These shares come from HS customs code 283990, which covers 20 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
MX 25%MexicoCA 17%CanadaDE 12%GermanyIT 12%ItalyJP 9%Japan
EPA-registered manufacturers (2)
Evonik
Shinagawa Americas
Domestic parents -- activity not disclosed (2)
Baerlocher Production
Pq
EPA-registered importers (6)
Azelis S A · LU Luxembourg
Azelis Americas Case
Master Builders Solutions
Rtx
Tenneco Brake
Show all 6
W. R. Grace & Co. - Conn.
5 FDA-registered drug labelers
Boiron
Hahnemann Laboratories, INC.
Kadesh Incoporation Co,Ltd
Liddell Laboratories
Nucleic Products, LLC

Why It Matters

Sectors
HealthTransportationConstructionPlastics & RubberConsumer ProductsPaints & CoatingsPaper & Printing
Downstream Uses

Appears in 10 drug and cosmetic product listings (FDA).

  • •Oxaltem
  • •Mineffect facial skin protectant and acne treatment solution
  • •MEB PainGuard Patch
  • •Calcarea Silicata
  • •Overwhelmed
  • •Mineffect hangover relief
  • •Mineffect skin protectant
  • •Mineffect acid indigestion and heartburn relief
Show all 10
  • •Mineffect first aid antiseptic and antibiotic solution
  • •Mineffect nasal mist
FDA Shortage Status
No FDA shortage records

Industrial Uses

Used in 6 sectors as 6 functional roles.

  • •Flow promoter in Not Known or Reasonably Ascertainable (100%)Processing—incorporation into article
  • •Anti-caking agent in Construction (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Filler in Paper Manufacturing (97%)Processing—incorporation into formulation, mixture, or reaction product
  • •Filler in Paint and Coating Manufacturing (3%)Processing—incorporation into formulation, mixture, or reaction product
  • •Pigment in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Filler in Transportation Equipment Manufacturing (100%)Processing—incorporation into article
  • •Wetting agent (non-aqueous) in Wholesale and Retail TradeNot Known or Reasonably Ascertainable
  • •Hardener in Wholesale and Retail Trade (0%)Not Known or Reasonably Ascertainable

Chemical Identity

CAS1344-95-2
PubChem CID73415800
DTXSIDDTXSID4029648
FormulaCaH6O8Si2
Mol. Weight230.29 g/mol
SMILESO[Si](O)(O)[O-].O[Si](O)(O)[O-].[Ca+2]

Data Sources

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Brief citations

Calcium silicate (CAS 1344-95-2) https://chemicalindependence.com/chemical/1344-95-2/ EPA CompTox (DSSTox): DTXSID4029648. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID4029648 PubChem: 73415800. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/73415800 EPA Chemical Data Reporting: 1344-95-2. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 1344-95-2. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 283990 for CAS 1344-95-2. Reporting year: 2024. https://usatrade.census.gov/