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Ephedrine sulfate

Drug ingredient

CAS 134-72-5

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 134-72-5
US productionNot reported
Import value, 2024$240K
Top sourceIndia 78%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293941 · basket

These shares come from HS customs code 293941, which covers 7 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IN 78%IndiaDE 22%Germany
32 FDA-registered drug labelers
Amneal Pharmaceuticals LLC
Caplin Steriles Limited
Civica, Inc.
CVS Pharmacy, Inc
Dr. Reddy's Laboratories, Inc.
Embio Limited
ENDO USA, Inc.
Eugia US LLC
Exela Pharma Sciences, LLC
Foundation Consumer Healthcare LLC
Fresenius Kabi USA, LLC
Gland Pharma Limited
HF Acquisition Co LLC, DBA HealthFirst
Hikma Pharmaceuticals USA Inc.
Lifestar Pharma LLC
Malladi Drugs & Pharmaceuticals Limited
Medical Purchasing Solutions, LLC
Nexus Pharamaceuticals Inc.
Nexus Pharmaceuticals, LLC
NorthStar Rx LLC
Par Health USA, LLC
Patheon Manufacturing Services LLC
Professional Compounding Centers of America dba PCCA
ProPharma Distribution
REMEDYREPACK INC.
Sagent Pharmaceuticals
Sandoz Inc
Siegfried PharmaChemikalien Minden GmbH
Somerset Therapeutics, LLC
Spectrum Laboratory Products, Inc.
Walgreen Company
Xiromed, LLC

Why It Matters

Sectors
Health
Downstream Uses

Appears in 5 drug and cosmetic product listings (FDA).

  • •Ephedrine Sulfate
  • •Emerphed
  • •Bronkaid Max
  • •Emerphed PFS
  • •Akovaz
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS134-72-5
PubChem CID5359318
DTXSIDDTXSID6020565
FormulaC20H32N2O6S
Mol. Weight428.5 g/mol
SMILESCC(C(C1=CC=CC=C1)O)NC.CC(C(C1=CC=CC=C1)O)NC.OS(=O)(=O)O

Data Sources

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Brief citations

Ephedrine sulfate (CAS 134-72-5) https://chemicalindependence.com/chemical/134-72-5/ PubChem: 5359318. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5359318 EPA TSCA Inventory: CAS 134-72-5. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293941 for CAS 134-72-5. Reporting year: 2024. https://usatrade.census.gov/