5-Methyltetrahydrofolic acid
Drug ingredientCAS 134-35-0
This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.
US productionNot reported
Top sourceNo public record
This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.
Why supply is unknownWhere It Comes From
EPA and Census publish no US supply data for this chemical.
1 FDA-registered drug labeler
Avion Pharmaceuticals, LLC
Why It Matters
Sectors
Health
Downstream Uses
Appears in 2 drug and cosmetic product listings (FDA).
- •Prenate Elite
- •Prenate Essential
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Chemical Identity
CAS134-35-0
PubChem CID135415868
DTXSIDDTXSID4048278
FormulaC20H25N7O6
Mol. Weight459.5 g/mol
SMILESCN1C(CNC2=C1C(=O)NC(=N2)N)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
Data Sources
- PubChem · compound 135415868Retrieved 2026-04-07
- FDA National Drug Code directoryRetrieved 2026-04-25
- FDA National Drug Code directoryRetrieved 2026-04-07
Brief citations
5-Methyltetrahydrofolic acid (CAS 134-35-0) https://chemicalindependence.com/chemical/134-35-0/ PubChem: 135415868. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/135415868 FDA National Drug Code directory: CAS 134-35-0. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/