Doravirine

Drug ingredient

CAS 1338225-97-0

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$907M

Top sourceIreland 47%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293379 · basket

These shares come from HS customs code 293379, which covers 105 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 47%IrelandBE 19%BelgiumSG 11%SingaporeIT 4%ItalyCH 4%Switzerland

Brazil
Canada
Taiwan
Ukraine
Portugal
Netherlands
South Korea
Israel
Czech Republic
Spain
Finland
Hungary
Malaysia
Australia
Austria
Slovenia

7 FDA-registered drug labelers

A-S Medication Solutions

F.I.S. FABBRICA ITALIANA SINTETICI S.P.A.

HETERO LABS LIMITED

Hovione FarmaCiencia SA

Matrix Pharmacorp Private Limited

Merck Sharp & Dohme LLC

MSD International GmbH

Why It Matters

Sectors

Health

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•Delstrigo
•Pifeltro

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$2503.00/gAngene Chemical

CountryChina (registered: Hong Kong)

Pack$2503.00 / 1 g

Purity98%

Vendors16 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

15 more vendors

Vendor	Country	$/g	Pack	Purity
Combi-Blocks (back-ordered)	United States	$2700.00	250 mg	95%
Aaron Chemicals LLC	Hong Kong	$2736.00	250 mg	98%
BLD Pharmatech Ltd.	China	$2892.00	250 mg	98%
Molnova	China	$2934.00	500 mg	99%
Ambeed, Inc.	United States	$3180.00	250 mg	98%
MedKoo Biosciences, Inc	United States	$3650.00	1 g	98%
A2B Chem LLC	United States	$4020.00	50 mg	99.79%
AA BLOCKS	United States	$4460.00	50 mg	99.79%
BLD Pharmatech Co., Limited	United States	$4490.00	100 mg	98%
BLD Pharmatech GmbH	Germany	$6520.00	25 mg	98%
TargetMol Chemicals	China → United States	$7890.00	100 mg	99.79%
MedChemExpress MCE	Sweden	$12378.30	100 mg	99.79%
Angene International Limited	United States	$16030.00	100 mg	98%
AstaTech (2 weeks)	United States	$17400.00	25 mg	98%
Cayman Europe	Estonia	$22610.00	10 mg	98%

Chemical Identity

CAS1338225-97-0

PubChem CID58460047

DTXSIDDTXSID30158386

FormulaC17H11ClF3N5O3

Mol. Weight425.7 g/mol

SMILESCN1C(=NNC1=O)CN2C=CC(=C(C2=O)OC3=CC(=CC(=C3)C#N)Cl)C(F)(F)F

Data Sources

PubChem · compound 58460047Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Doravirine (CAS 1338225-97-0) https://chemicalindependence.com/chemical/1338225-97-0/ PubChem: 58460047. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/58460047 FDA National Drug Code directory: CAS 1338225-97-0. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293379 for CAS 1338225-97-0. Reporting year: 2024. https://usatrade.census.gov/