insulin lispro
Drug ingredientThis chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.
Where It Comes From
7 FDA-registered drug labelers
A-S Medication Solutions
Eli Lilly and Company
Eli Lilly Italia SPA
Lilly del Caribe, Inc.
Lilly France
REMEDYREPACK INC.
Sanofi-Aventis U.S. LLC
Why It Matters
Sectors
Health
Downstream Uses
Appears in 16 drug and cosmetic product listings (FDA).
- •Humalog
- •Lyumjev
- •Lyumjev KwikPen
- •Insulin Lispro KwikPen
- •Humalog KwikPen
- •Insulin Lispro
- •Admelog
- •Lyumjev Tempo Pen
Show all 16
- •Lyumjev Junior KwikPen
- •Humalog Mix75/25
- •Humalog Tempo Pen
- •Humalog Mix75/25 KwikPen
- •Humalog Junior KwikPen
- •Insulin Lispro Junior KwikPen
- •Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 KwikPen
- •Humalog Mix50/50 KwikPen
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No Shortage
Shortage History
Each row is a separate manufacturer's FDA shortage filing — not a timeline for the drug as a whole. Multiple "current" entries are normal: each manufacturer/NDC files independently. Status reflects the manufacturer's report; reason describes their supply situation (Available, Unavailable, or to be discontinued).
to be discontinued
Insulin Lispro-aabc Injection
10/24/2025to be discontinued
Insulin Lispro Injection
10/24/2025Chemical Identity
CAS133107-64-9
PubChem CID16132438
DTXSIDDTXSID90157956
FormulaC257H389N65O77S6
Mol. Weight5814 g/mol
SMILESCCC(C)C(C(=O)NC(C(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CS)C(=O)NC(CS)C(=O)NC(C(C)O)C(=O)NC(CO)C(=O)NC(C(C)CC)C(=O)NC(CS)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)N)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CS)C(=O)NC(CC(=O)N)C(=O)O)NC(=O)CN.CC(C)CC(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CS)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CC2=CC=CC=C2)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=CC=C(C=C4)O)C(=O)NC(C(C)O)C(=O)NC(CCCCN)C(=O)N5CCCC5C(=O)NC(C(C)O)C(=O)O)NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC6=CN=CN6)NC(=O)C(CO)NC(=O)CNC(=O)C(CS)NC(=O)C(CC(C)C)NC(=O)C(CC7=CN=CN7)NC(=O)C(CCC(=O)N)NC(=O)C(CC(=O)N)NC(=O)C(C(C)C)NC(=O)C(CC8=CC=CC=C8)N
Data Sources
161324382026-04-07
https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/name/insulin lispro/cids/JSON
Archive: data/sources/pubchem_name/insulin lispro.json
CAS 133107-64-92026-04-25
https://open.fda.gov/data/ndc/
Archive: data/sources/fda/ndc/ndc.json
CAS 133107-64-92026-06-13
https://api.fda.gov/drug/shortages.json
Archive: data/sources/fda/shortages/shortages.json