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Pheniramine maleate

Drug ingredient

CAS 132-20-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 132-20-7
US productionNot reported
Import value, 2024$1.3B
Top sourceChina 32%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293339 · basket

These shares come from HS customs code 293339, which covers 397 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 32%ChinaIN 15%IndiaDE 10%GermanyBE 9%BelgiumCH 8%Switzerland
17 FDA-registered drug labelers
A-S Medication Solutions
Alcon Laboratories, Inc.
Altaire Pharmaceuticals Inc.
AX Pharmaceutical Corp
Bausch & Lomb Incorporated
CVS PHARMACY
DOLGENCORP, LLC
Kenvue Brands LLC
Keshava Organics Pvt Ltd
Kongo Chemical Co., Ltd.
Poly Pharmaceuticals, Inc.
Rite Aid Corporation
Spectrum Laboratory Products, Inc.
Supriya Lifescience Limited
Target Corporation
Wal-Mart Stores Inc
Walgreen Company

Why It Matters

Sectors
Health
Downstream Uses

Appears in 7 drug and cosmetic product listings (FDA).

  • •Naphcon A
  • •Eye Allergy Relief
  • •Naphazoline HCI And Pheniramine Maleate
  • •Opcon-A
  • •Visine Allergy Eye Relief Multi-Action
  • •Alahist D
  • •Alahist DM
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS132-20-7
PubChem CID5282139
DTXSIDDTXSID0025866
FormulaC20H24N2O4
Mol. Weight356.4 g/mol
SMILESCN(C)CCC(C1=CC=CC=C1)C2=CC=CC=N2.C(=CC(=O)O)C(=O)O

Data Sources

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Brief citations

Pheniramine maleate (CAS 132-20-7) https://chemicalindependence.com/chemical/132-20-7/ PubChem: 5282139. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5282139 EPA TSCA Inventory: CAS 132-20-7. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293339 for CAS 132-20-7. Reporting year: 2024. https://usatrade.census.gov/