Cupric oxide
Drug ingredientCAS 1317-38-0
This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$32M
Top sourceNorway 50%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 282550 · narrow
EPA reports by year
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
These shares come from HS customs code 282550, which covers 3 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
Source Countries
Country of origin for US imports, from Census customs data (2024).
NO 50%NorwayAU 31%AustraliaDE 5%GermanyIT 5%ItalyMX 4%Mexico
- China
- India
- Canada
- Hong Kong
- South Korea
- Netherlands
EPA-registered manufacturers (24)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Basf Se · DE Germany
Clariant International · CH Switzerland
Oci N V · NL Netherlands
Rag-Stiftung · DE Germany
Rio Tinto Plc · GB United Kingdom
Show all 24
Wieland-Werke Ag · DE Germany
Agmet
American Chemet
Basf
Clariant
Condy Holdings
Essex Furukawa Magnet Wire
Evonik
Iowa Intermediate Fertilizer Holding
Koch Industries
Langeloth Metallurgical
Nib
Phibro Animal Health
Revere Copper Products
Rio Tinto America
Steel Dust Recycling
Venator Chemicals
Wieland Holdings
Wsp
Domestic parents -- activity not disclosed (2)
EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.
Bluestone Specialty Chemicals
Honeywell International (123312)
EPA-registered importers (10)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Basf Se · DE Germany
Clariant International · CH Switzerland
Umicore Sa · BE Belgium
Adchem (Australia) Pty
Air Products And Chemicals
Show all 10
Atotech Manufacturing
Cameron Chemical
Johnson Matthey
Penn A Kem
Umicore Usa
15 FDA-registered drug labelers
A-S Medication Solutions
Acella Pharmaceuticals, LLC
Avion Pharmaceuticals, LLC
Bestmade Natural Products
Boiron
BonGeo Pharmaceuticals, Inc.
Exeltis USA, Inc.
Hahnemann Laboratories, INC.
Jost Chemical Co.
Mission Pharmacal Company
OHM PHARMA INC.
Patrin Pharma, Inc.
PEKANA Naturheilmittel GmbH
REMEDYREPACK INC.
Uriel Pharmacy Inc.
Why It Matters
Sectors
HealthAgricultureFoodEnergyWaterElectronicsTransportationConstructionMetals & MiningPlastics & RubberPaints & CoatingsCore Chemicals
Downstream Uses
Appears in 14 drug and cosmetic product listings (FDA).
- •Floriva
- •Vitafol Fe Plus
- •Cuprum Oxydatum Nigrum
- •OHM Parasites
- •Prenatal Vitamins Plus Low Iron
- •Prenate Elite
- •Bestmade Natural Products BM43
- •PNV-Select
Show all 14
- •CitraNatal 90 DHA
- •Vitafol Ultra
- •Prenatal Plus Vitamins
- •Nicomide
- •Copper Oxide 0.4
- •Helmin
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
Used in 20 sectors as 10 functional roles.
- •Soil amendments (fertilizers) in Agriculture, Forestry, Fishing and Hunting (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Soil amendments (fertilizers) in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (20%)Processing as a reactant
- •Adsorbent in Oil and Gas Drilling, Extraction, and Support activitiesUse—non-incorporative activities
- •Adsorbent in All Other Basic Inorganic Chemical ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Catalyst in All Other Basic Organic Chemical ManufacturingUse—non-incorporative activities
- •Pigment in Non-metallic Mineral Product Manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other non-metallic mineral product manufacturing) (100%)Processing—incorporation into article
- •Catalyst in All Other Basic Inorganic Chemical ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Catalyst in Petrochemical ManufacturingUse—non-incorporative activities
- •Plating agent in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Catalyst in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (100%)Processing as a reactant
- •Catalyst in All Other Chemical Product and Preparation Manufacturing (10%)Use—non-incorporative activities
- •Catalyst in Services (86%)Use—non-incorporative activities
- •Catalyst in Electrical Equipment, Appliance, and Component Manufacturing (3%)Use—non-incorporative activities
- •Catalyst in Industrial Gas Manufacturing (100%)Use—non-incorporative activities
- •Oxidizing agent in Other (17%)Processing—incorporation into formulation, mixture, or reaction product
- •Oxidizing agent in Industrial Gas Manufacturing (60%)Processing—incorporation into formulation, mixture, or reaction product
- •Oxidizing agent in Utilities (24%)Processing—incorporation into formulation, mixture, or reaction product
- •Alloys in Other (10%)Processing—incorporation into article
- •Alloys in Primary Metal Manufacturing (10%)Processing—repackaging
- •Adsorbent in Industrial Gas Manufacturing (0%)Use—non-incorporative activities
- •Catalyst in Food, beverage, and tobacco product manufacturing (1%)Use—non-incorporative activities
- •Catalyst in Petroleum Refineries (2%)Use—non-incorporative activities
- •Adsorbent in All Other Chemical Product and Preparation Manufacturing (1%)Use—non-incorporative activities
- •Adsorbent in Petroleum Refineries (1%)Use—non-incorporative activities
- •Intermediate in Primary Metal Manufacturing (100%)Processing as a reactant
- •Catalyst in All other Petroleum and Coal Products ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Preservative in Pesticide, Fertilizer, and Other Agricultural Chemical ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Flavoring and nutrient in Pesticide, Fertilizer, and Other Agricultural Chemical ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Adsorbent in Plastics Material and Resin Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Catalyst in Plastics Material and Resin ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Catalyst in Transportation Equipment ManufacturingProcessing—incorporation into article
Chemical Identity
CAS1317-38-0
PubChem CID164827
DTXSIDDTXSID5034488
FormulaCuO
Mol. Weight79.55 g/mol
SMILES[O-2].[Cu+2]
Data Sources
- EPA CompTox (DSSTox) · DTXSID5034488Retrieved 2026-04-06
- PubChem · compound 164827Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- FDA National Drug Code directoryRetrieved 2026-04-07
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Cupric oxide (CAS 1317-38-0) https://chemicalindependence.com/chemical/1317-38-0/ EPA CompTox (DSSTox): DTXSID5034488. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID5034488 PubChem: 164827. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/164827 EPA Chemical Data Reporting: 1317-38-0. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 1317-38-0. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 282550 for CAS 1317-38-0. Reporting year: 2024. https://usatrade.census.gov/