Upadacitinib

Drug ingredient

CAS 1310726-60-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 1310726-60-3
US productionNot reported
Import value, 2024$1.4B
Top sourceIreland 33%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293399 · basket

These shares come from HS customs code 293399, which covers 518 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 33%IrelandCN 26%ChinaIN 11%IndiaDE 9%GermanyIT 4%Italy
7 FDA-registered drug labelers
AbbVie Inc.
AbbVie Ireland NL B.V.
AbbVie SRL
Aurobindo Pharma Limited
Curia Spain S.A.U.
HONOUR LAB LIMITED
MSN Laboratories Private Limited

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Rinvoq
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$38.16/gAngene Chemical
CountryChina (registered: Hong Kong)
Pack$954.00 / 25 g
Purity99%
Vendors20 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS1310726-60-3
PubChem CID58557659
DTXSIDDTXSID901027919
FormulaC17H19F3N6O
Mol. Weight380.4 g/mol
SMILESCCC1CN(CC1C2=CN=C3N2C4=C(NC=C4)N=C3)C(=O)NCC(F)(F)F

Data Sources

Brief citations

Upadacitinib (CAS 1310726-60-3) https://chemicalindependence.com/chemical/1310726-60-3/ PubChem: 58557659. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/58557659 FDA National Drug Code directory: CAS 1310726-60-3. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293399 for CAS 1310726-60-3. Reporting year: 2024. https://usatrade.census.gov/