1,5-Naphthalenedisulfonic acid, 3-amino-

CAS 131-27-1

Companies reported imports and no US production of this chemical to EPA for 2023.

US productionZero

Import value, 2024$2M

Import volume11.5K lb

Import dependency100%

Top sourceCanada 48%

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

1,5-Naphthalenedisulfonic acid, 3-amino- · US import value by year

2013: $9M · Peak 2021: $18M · 2024: $2M · 2025: $2M

Where It Comes From

Customs basis: HS 292145 · basket

EPA reports by year

2023: US production Zero · Imports 11.5K lb
2019: US production Zero · Imports 1 lb

These shares come from HS customs code 292145, which covers 23 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CA 48%CanadaIN 35%IndiaCN 10%ChinaCH 7%SwitzerlandJP 1%Japan

EPA-registered importers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Atul Usa

Why It Matters

Sectors

Core Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in All Other Basic Organic Chemical ManufacturingProcessing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.17/gAaron Chemicals LLC

CountryHong Kong

Pack$86.00 / 500 g

Purity95%

Vendors15 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

14 more vendors

Vendor	Country	$/g	Pack	Purity
BLD Pharmatech GmbH	Germany	$0.20	500 g	95%
BLD Pharmatech Ltd.	China	$0.20	500 g	95%
Angene Chemical	China → Hong Kong	$0.20	500 g	—
BLD Pharmatech Co., Limited	United States	$0.22	500 g	95%
Ambeed, Inc.	United States	$0.22	500 g	95%
A2B Chem LLC	United States	$0.25	100 g	95%
Combi-Blocks, Inc.	United States	$0.25	1 kg	95%
AA BLOCKS	United States	$0.27	100 g	95%
AK Scientific, Inc.	United States	$1.16	25 g	95%
Angene International Limited	United States	$3.20	25 g	95%
Vitas M Chemical Limited	Hong Kong	$3170.00	100 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	95%
Princeton BioMolecular Research (SC)	United States	$5000.00	30 mg	90%
Asinex	Netherlands	$6461.40	100 mg	90%

Chemical Identity

CAS131-27-1

PubChem CID8563

DTXSIDDTXSID5059616

FormulaC10H9NO6S2

Mol. Weight303.3 g/mol

SMILESC1=CC2=C(C=C(C=C2S(=O)(=O)O)N)C(=C1)S(=O)(=O)O

Data Sources

EPA CompTox (DSSTox) · DTXSID5059616Retrieved 2026-04-06
PubChem · compound 8563Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

1,5-Naphthalenedisulfonic acid, 3-amino- (CAS 131-27-1) https://chemicalindependence.com/chemical/131-27-1/ EPA CompTox (DSSTox): DTXSID5059616. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID5059616 PubChem: 8563. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/8563 EPA Chemical Data Reporting: 131-27-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 131-27-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292145 for CAS 131-27-1. Reporting year: 2024. https://usatrade.census.gov/